沈阳地区成人血清和脐带血中全氟有机物污染现状

目的　了解沈阳地区一般人群血清和脐带血中全氟辛烷磺酸 (PFOS)和全氟辛酸 (Perfluorooctanoicacid,PFOA)污染现状。方法　采用液相色谱 质谱仪联机选择性监测离子法 (PFOS :m z =4 99,PFOA :m z =4 1 3) ,测定脐带血和被调查者血清中PFOS和PFOA浓度。结果　男女血清中PFOS和PFOA浓度几何均数分别为 4 0 73μg L和 4 5 4 6 μg L、1 1 5 3μg L和 8 97μg L- 1 。脐带血中PFOS和PFOA浓度几何均数分别为2 2 1 4 μg L和 0 2 6 4 μg L。成人血清和脐带血中PFOS和PFOA浓度与年龄无关相关性 (p <0 0 5 )。 结论　一般人群体内也存在PFOS污染物 ,而且血清PFOS浓度高于美国人和日本人水平。人类脐带血中也存在PFOS和PFOA污染

Status of perfluorochemicals in adult serum and umbilical blood in Shenyang

OBJECTIVE: To study the status of perfluorooctane sulfonate (PFOS), and Perfluorooctanoic acid (FOA) pollution in serum and umbilical blood among general people in Shenyang area. METHODS: Concentration of PFOS and PFOA in adult serum and umbilical blood samples was measured by means of liquid phase chromatography/mass spectrograph selective iron monitoring (PFOS: m/z = 499, PFOA: m/z = 413). RESULTS: It was showed that geometric mean of serum concentration of PFOS of male was 40.73microg/L and that of female was 45.46microg/L, PFOA is 11.53microg/L and 8.97microg/L. Geometric mean concentration of PFOS and PFOA in umbilical blood was 2.214microg/L and 0.264microg/L. There was no correlativity between concentration of PFOS, PFOA and age in adult serum and umbilical blood. CONCLUSION: It was suggested that there was PFOS contamination in common group in Shenyang. Also, fetus was exposed in PFOS and PFOA during its embryonic period. There were also PFOS and PFOA pollution in human umbilical blood samples.