Effectiveness of high implantation of SAPIEN 3 in preventing pacemaker implantation: A propensity score analysis |
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Affiliation: | 1. Department of Cardiology, Kawasaki Heart Centre, Kawasaki Saiwai Hospital, Saiwai-ku, Kawasaki-shi, 212-0014 Kanagawa, Japan;2. Department of Computer and Information Science, Faculty of Science and Technology, Seikei University, Musashino-shi, 180-8633 Tokyo, Japan;3. School of Statistical Thinking, The Institute of Statistical Mathematics, Tachikawa, 190-8562 Tokyo, Japan |
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Abstract: | BackgroundIn transcatheter aortic valve implantation, high implantation on the aortic annulus may prevent conduction pathway injury, leading to a decrease in the rate of permanent pacemaker implantation.AimTo assess the impact of high implantation of SAPIEN 3 on the prevention of permanent pacemaker implantation.MethodsSince August 2020, we have performed high implantation by fluoroscopically positioning the lower part of the lucent line at the virtual basal ring line on a coplanar view before valve implantation. Patients treated before the adoption of this method were defined as the conventional group. We compared the high implantation group with the conventional group using propensity score analysis.ResultsOverall, the high implantation group (n = 95) showed a significantly shorter ventricular strut length than the conventional group (n = 85): median 1.3 (interquartile range 0.2–2.4) mm vs 2.8 (1.8–4.1) mm (P < 0.001). The permanent pacemaker implantation rate was significantly lower in the high implantation group than in the conventional group (2.1% vs 11.8%; P = 0.009). According to 100 propensity score analyses based on multiple imputation and the selection of appropriate covariates, the median P value for the comparison of permanent pacemaker implantation rates after transcatheter aortic valve implantation between the high implantation group and the conventional group ranged between 0.001 and 0.017, indicating a more significant reduction in the permanent pacemaker implantation rate in the high implantation group than in the conventional group. Neither valve dislodgement nor the need for a second valve was observed in either group.ConclusionsThe high implantation of SAPIEN 3 successfully decreases ventricular strut length, reducing the permanent pacemaker implantation rate after transcatheter aortic valve implantation. |
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Keywords: | Transcatheter aortic valve implantation Balloon-expandable aortic valve High implantation Pacemaker prevention Propensity score analysis AS" },{" #name" :" keyword" ," $" :{" id" :" kw0035" }," $$" :[{" #name" :" text" ," _" :" aortic stenosis CT" },{" #name" :" keyword" ," $" :{" id" :" kw0045" }," $$" :[{" #name" :" text" ," _" :" computed tomography IPTW" },{" #name" :" keyword" ," $" :{" id" :" kw0055" }," $$" :[{" #name" :" text" ," _" :" inverse probability of treatment weighting PPI" },{" #name" :" keyword" ," $" :{" id" :" kw0065" }," $$" :[{" #name" :" text" ," _" :" permanent pacemaker implantation RBBB" },{" #name" :" keyword" ," $" :{" id" :" kw0075" }," $$" :[{" #name" :" text" ," _" :" right bundle branch block STS" },{" #name" :" keyword" ," $" :{" id" :" kw0085" }," $$" :[{" #name" :" text" ," _" :" Society of Thoracic Surgeons TAVI" },{" #name" :" keyword" ," $" :{" id" :" kw0095" }," $$" :[{" #name" :" text" ," _" :" transcatheter aortic valve implantation |
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