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Enforced expression of Runx3 improved CAR-T cell potency in solid tumor via enhancing resistance to activation-induced cell death |
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| Affiliation: | 1. State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200032, China;2. CARsgen Therapeutics Co., Ltd, Shanghai 200231, China;3. CARsgen Life Sciences Co., Ltd, Shanghai 200231, China;4. Crown Bioscience, Inc, Santa Clara, CA 95050, USA |
| Abstract: |  |
| Keywords: | Runx3 CAR-T therapy hepatocellular carcinoma TNF AICD |
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