Hypophosphatemia and acute respiratory failure in a diabetic patient |
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| Authors: | Dr. L. Hasselstrøm P. D. Wimberley V. G. Nielsen |
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| Affiliation: | (1) Department of Anaesthesia, Herlev Hospital, University of Copenhagen, Denmark;(2) Department of Clinical Chemistry, Herlev Hospital, University of Copenhagen, Denmark;(3) Department of Anaesthesia, Randers Centralsygehus, DK-8900 Randers, Denmark |
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| Abstract: | A previously healthy 48-year-old male developed diabetic ketoacidosis and severe hypophosphatemia. Within a few hours, acute respiratory insufficiency developed with a marked discrepancy between the pulmonary pathology and the very poor oxygenation seen. We argue that this was due to the effect of hypophosphatemia on respiratory muscle- and heart function and P50, leading to impaired oxygen delivery. |
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| Keywords: | Hypophosphatemia Acute respiratory failure Oxyhemoglobin dissociation curve |
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