| 宫颈阴道分泌物中的胰岛素样生长因子结合蛋白-1诊断胎膜早破 |
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| 引用本文： | 谌小卫,张新玲,范建辉,尹玉竹,李小毛. 宫颈阴道分泌物中的胰岛素样生长因子结合蛋白-1诊断胎膜早破[J]. 中国现代医学杂志, 2002, 12(6): 3-4 |
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| 作者姓名： | 谌小卫 张新玲 范建辉 尹玉竹 李小毛 |
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| 作者单位： | 中山大学附属第三医院妇产科,广州,510630 |
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| 摘 要： | 目的 :探讨宫颈阴道分泌物中的胰岛素样生长因子结合蛋白 - 1(IGFBP - 1)在胎膜早破诊断中的价值。方法 :选择 2 0 4例胎膜早破孕妇和 89例正常孕妇 ,应用免疫层析法对其宫颈阴道分泌物进行IGFBP - 1检测。结果 :IGFBP - 1诊断胎膜早破的敏感性 94 .2 % ,特异性 93.4 % ,阳性预测值 97.0 % ,阴性预测值 93.2 %。结论 :宫颈阴道分泌物中的IGFBP - 1可作为诊断胎膜早破的客观指标 ,对临床有较大的实用价值。
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| 关 键 词： | 胰岛素样生长因子结合蛋白-1(IGFBP-1) 宫颈阴道分泌物 胎膜早破 |
| 修稿时间： | 2002-01-20 |
VALUE OF THE INSULIN LIKE GROWTH FACTOR BINDING PROTEIN-1 IN CERVICOVAGINAL SECRETIONS FOR THE DIAGNOSIS OF PREMATURE RUPTURE OF MEMBRANE |
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| Chen Xiaowei,Zhang Xinling,Fan Jianhui,et al.. VALUE OF THE INSULIN LIKE GROWTH FACTOR BINDING PROTEIN-1 IN CERVICOVAGINAL SECRETIONS FOR THE DIAGNOSIS OF PREMATURE RUPTURE OF MEMBRANE[J]. China Journal of Modern Medicine, 2002, 12(6): 3-4 |
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| Authors: | Chen Xiaowei Zhang Xinling Fan Jianhui et al. |
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| Affiliation: | Chen Xiaowei,Zhang Xinling,Fan Jianhui,et al. Department of Obstetrics and Gynecology,the 3rd Affiliated Hospital of Sun Yat_Sen University,Guangzhou 510630$$$$ |
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| Abstract: | Objective:To study the value of insulin like growth factor binding protein-1 (IGFBP-1) in cervicovaginal secretions for the diagnosis of premature rupture of membrane (PROM).Methods:Two hundred and four cases of ruptured amniotic membranes and 89 cases of term pregnancy took part in our prospective study.IGFBP-1 in cervicovaginal secretions was measured by immunochromatography methods.Result:As a predictor for the diagnosis of PROM,IGFBP-1 had a sensitivity of 94.2%,a specificity of 93.4%,a predictive value of the positive test 97.0% and a predictive value of the negative test 93.2%.Conclusion:Insulin like growth factor binding protein_1 can be used as an objective indicator in the diagnosis of premature rupture of membrane. |
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| Keywords: | Insulin Like Growth Factor Binding Protein_1 Cervicovaginal Secretions Premature Rupture of Membrane |
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