| 基于苦味产生机制的掩味策略与评价 |
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| 引用本文： | 任树龙,王亚静,郑银,孟亚飞,邓新焕.基于苦味产生机制的掩味策略与评价[J].中南药学,2014(6):562-566. |
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| 作者姓名： | 任树龙 王亚静 郑银 孟亚飞 邓新焕 |
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| 作者单位： | [1]天津中医药大学,天津300193; [2]天津市现代中药重点实验室省部共建国家重点实验室培育基地,天津300193; [3]现代中药发现与制剂技术教育部工程研究中心,天津300193 |
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| 基金项目： | 天津市科技支撑计划重点项目（No.12ZCZDJC35700）; 国家科技部“重大新药创制”专项课题（No.2012ZX09304007） |
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| 摘 要： | 口服制剂中许多药物尤其是中药常常会由于不良口味的影响,致使患者的顺应性降低,限制了临床应用。文章以苦味产生机制为主线,综述目前药物掩味技术的原理、特点和制备过程,并简述掩味技术评价方法的最新进展。
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| 关 键 词： | 苦味机制 掩味技术 掩味评价 |
Taste masking and evaluation based on the mechanism of bitterness |
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| Institution: | REN Shu-long, WANG Ya-jing , ZHENG Yin, MENG Ya-fei, DENG Xin-huan (1. Tianjin University of Tra ditional Chinese Medicine, Tianjin 300193; 2. Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin 300193; 3. Engineering Research Center of Modern Chinese Medicine Discovery and Prepartion Tech- nique, Ministry of Education, Tianjin 300193) |
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| Abstract: | Clinical applications of some oral administration medicine, especially Chinese material medicine, are limited by their unpleasant taste. The mechanism of bitterness and taste masking was reviewed. Different taste masking evaluation methods were summarized. |
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| Keywords: | mechanism of bitterness taste masking technology taste masking evaluation |
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