| 咀嚼刺激调节机体应激神经机制的研究进展 |
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| 引用本文： | 肖凡,苏俭生,韩雯斐.咀嚼刺激调节机体应激神经机制的研究进展[J].口腔颌面外科杂志,2020,30(1):42-46. |
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| 作者姓名： | 肖凡 苏俭生 韩雯斐 |
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| 作者单位： | 上海牙组织修复与再生工程技术研究中心,同济大学口腔医学院·附属口腔医院口腔修复教研室,上海 200072 |
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| 基金项目： | 国家自然科学基金面上项目(81671014、81572114、81873715) |
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| 摘 要： | 应激源激活下丘脑、蓝斑、杏仁核和海马等核团,诱发机体功能紊乱及相关的病理变化,表现出紧咬牙、咬甲癖、磨牙症,甚至颞下颌关节紊乱等口颌系统症状。三叉神经感觉及运动核团能调控咀嚼的口腔感受及咀嚼肌运动,并参与应激状态下的机体反应。本综述就中枢神经系统对应激的研究做了概括,并且总结了咀嚼刺激对于机体应激状态的正性调节作用,以期探讨压力应激下口颌系统的生理、病理反应的潜在发病机制,从而进一步指导临床治疗。
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| 关 键 词： | 应激 咀嚼 中枢神经系统 三叉神经核团 |
A Review on the Mechanism of How Chewing Impacts on the Central Nervous System under Stress |
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| XIAO Fan,SU Jiansheng,HAN Wenfei.A Review on the Mechanism of How Chewing Impacts on the Central Nervous System under Stress[J].Chinese Journal of Oral and Maxillofacial Surgery,2020,30(1):42-46. |
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| Authors: | XIAO Fan SU Jiansheng HAN Wenfei |
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| Institution: | (Department of Prosthodontics,School and Hospital of Stomatology,Tongji University,Shanghai Engineering Research Center of Tooth Restoration and Regeneration,Shanghai 200072,China) |
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| Abstract: | The stressor activates HPA axis,locus coeruleus,amygdala and hippocampus to induce a serious of physiological and pathological reactions as well as functional disorders.In maxillofacial system,the symptoms related to chew or bite such as teeth clenching,nail biting,and bruxism may be induced by stress.As the most important nucleus involving in the movement and sensation of chewing,the trigeminal system participates in the stress responses.This review focuses on central nervous system regulating mastication as a stress coping reaction.It will bring insight to the pathogenesis of stress induced maxillofacial disorders,and may provide advices for clinical practice. |
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| Keywords: | stress chewing central nervous system trigeminal nucleus |
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