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小牛血去蛋白提取物对胃溃疡患者的疗效评价
引用本文:才宁,王洪新,闫飞,王志义,禹向国,唐一超. 小牛血去蛋白提取物对胃溃疡患者的疗效评价[J]. 中国临床药理学与治疗学, 2003, 8(3): 314-316
作者姓名:才宁  王洪新  闫飞  王志义  禹向国  唐一超
作者单位:1. 锦州医学院生物技术研究所,锦州,121001,辽宁
2. 锦州监狱医院内科,锦州,121001,辽宁
3. 锦州石化公司职工医院内科,锦州,121001,辽宁
摘    要:目的:探讨小牛血去蛋白提取物(DCBE)对胃溃疡的治疗作用。方法:选择年龄20~70岁之间,经胃镜检查确诊为活动期胃溃疡的住院患60例。治疗组32例采用静脉滴注DCBE(800mg,qd)和法莫替丁(100mg,bid)治疗;对照组28例采用静脉滴注法莫替丁(100mg,bid)单独治疗。用药2、4wk行胃镜检查,观察自觉缓解症状、时间、愈合率和总有效率。结果:治疗组自觉症状缓解时间明显缩短;给药后2、4wk治疗组及对照组胃镜检查溃疡愈合率分别为78.1%,46.4%及84.4%,71.4%。结论:DCBE能显促进胃溃疡的愈合。

关 键 词:小牛血去蛋白提取物 胃溃疡 疗效 药效学 法莫替丁
文章编号:1009-2501(2003)03-0314-03
修稿时间:2002-10-31

Efficacy of deproteinised calf blood extract in treatment of patients with peptic ulcer disease
CAI Ning,WANG Hong-Xin,YAN Fei ,WANG Zhi-Yi ,YU Xiang-Guo ,TA NG Yi-Chao Bio-Technology Institute,Jinzhou Medical College,Jinzhou ,Liaoning. Efficacy of deproteinised calf blood extract in treatment of patients with peptic ulcer disease[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2003, 8(3): 314-316
Authors:CAI Ning  WANG Hong-Xin  YAN Fei   WANG Zhi-Yi   YU Xiang-Guo   TA NG Yi-Chao Bio-Technology Institute  Jinzhou Medical College  Jinzhou   Liaoning
Affiliation:CAI Ning,WANG Hong-Xin,YAN Fei 1,WANG Zhi-Yi 2,YU Xiang-Guo 2,TA NG Yi-Chao 2Bio-Technology Institute,Jinzhou Medical College,Jinzhou 121001,Liaoning, 1 Department of Medicine,Prison Hospital,Jinzhou 121001,Liaoning, 2 D epartment of Medicine,Shihua Hospital,Jinzhou 121001,Liaoning
Abstract:AIM: To observe the efficacy of deproteinise d calf blood extract (DCBE) in the treatment of patients with peptic ulcer disease . METHODS: 60 patients were randomly divided into two groups. Tr eating group (n=32) received DCBE (800 mg, qd) and famotidine (1 00 mg, bid) and control group (n=28) received famotidine (100 mg /bid). These treatments lasted for four weeks. The efficacy was determined by ga stroendoscopy. RESULTS: The ulcer healing rates were 78.1 % and 46.4 % for 2 wk, and 84.4 % and 71.4 % for 4 wk in treating grou p and control group, respectively. CONCLUSION: DCBE has a signif icant effect in the treatment of patients with peptic ulcer disease.
Keywords:pharmacodynamics  deproteinised calf blood extract  famotidine  peptic ulcer
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