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视网膜母细胞瘤眼球摘除术后放射治疗效果探讨
引用本文:汪素萍,薛林英,嵇训传,褚仁远,步时伦,蒋秀丽,刘谆诗. 视网膜母细胞瘤眼球摘除术后放射治疗效果探讨[J]. 复旦学报(医学版), 1993, 0(6)
作者姓名:汪素萍  薛林英  嵇训传  褚仁远  步时伦  蒋秀丽  刘谆诗
作者单位:上海医科大学眼耳鼻喉科医院眼科(汪素萍,嵇训传,褚仁远),上海医科大学眼耳鼻喉科医院放疗科(薛林英),上海医科大学眼耳鼻喉科医院计算机室(步时伦,蒋秀丽),上海医科大学眼耳鼻喉科医院眼科(刘谆诗)
摘    要:通过对325例视网膜母细胞瘤(Rb)患者的随访和分析,其中56例视神经断端有Rb细胞残留(阳性)和269例视神经断端无Rb细胞残留(阴性)。两组经眼球摘除加放射治疗(放疗)或仅眼球摘除两种不同治疗,5a以上存活率比较差别无意义。而56例视神经断端阳性病例,放疗对抑制局部Rb复发是有效的,显示差别有显著意义。对估计眶内有Rb细胞残留者加用放疗,否则就不必以放疗作为常规治疗方法,以免因放疗造成后患。

关 键 词:视网膜母细胞瘤  眼球 摘除术  放射治疗  视神经

RADIOTHERAPEUTIC EFFECTS ON PATIENTS WITH RESIDUAL RETINOBLASTOMA CELLS AFTER ENUCLEATION
Wang Su-Ping,Xue Lin-Ying,Ji Xun-Ohuan,chu Een-Yuan,Bu Shi-Lun,Jiang Xiu-Li,Liu Ohun-Shi. RADIOTHERAPEUTIC EFFECTS ON PATIENTS WITH RESIDUAL RETINOBLASTOMA CELLS AFTER ENUCLEATION[J]. Fudan University Journal of Medical Sciences, 1993, 0(6)
Authors:Wang Su-Ping  Xue Lin-Ying  Ji Xun-Ohuan  chu Een-Yuan  Bu Shi-Lun  Jiang Xiu-Li  Liu Ohun-Shi
Abstract:825 cases of retinoblastoma (Rb) were followed up for more than 5 years. Among them, 56 cases had residual Rb cell at the cut end of the optic nerve (positive) and 269 cases were without (negative). They were treated by enucleation plus radiotherapy or simple enucleation. There was no significant difference in the survival rate of between the two groups after more than 5 years. But the 56 cases that had residual Eb cells treated by the above two different therapies showed statistically significant differences in the inhibit of local Eb recurrence. Therefore, radiotherapy is necessary that cages have residual Eb cell at the cut end of the optic nerve and in the orbit after enucleation, but unnecessary if the cases have no remaining Eb cells after enucleation.
Keywords:retinoblastoma  enueleation  radiotherapy  optic nerve
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