Micromanipulation of gametes and pre-implantation mammalian embryos--a review

With the successful management of the in vitro fertilization and embryo transfer in humans and in several mammalians it became possible to introduce further methods of the cellbiology in the practice. One complex in this connection is hereby shown to be the micromanipulation on gametes and on preimplantative embryos. With this technique the way was opened for some procedures which are known as microfertilization, transplantation of the nucleus and gene transfer somatic gene therapy. With these experiments a broad field of possibilities would be opened although about these can be only speculated.