Presence of pili on the surface of Francisella tularensis |
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| Authors: | Gil Horacio Benach Jorge L Thanassi David G |
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| Affiliation: | Department of Molecular Genetics and Microbiology, Stony Brook University, Stony Brook, New York 11794-5120, USA. |
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| Abstract: | Francisella tularensis is a highly infectious gram-negative bacterium with potential for use as a bioweapon. Analysis of the F. tularensis live vaccine strain (LVS) ultrastructure by electron microscopy revealed the presence of long, thin fibers, similar in appearance to type 4 pili. The highly virulent F. tularensis Schu S4 strain was found to contain type 4 pilus genes, and we confirmed that these genes are present and expressed in the LVS. |
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