| 抗甲状腺药物诱导的狼疮样综合征循证诊断与治疗的个案分析 |
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| 引用本文： | 杨立川,肖艰,李孜,苏白海,冀玲,刘先蓉,樊均明. 抗甲状腺药物诱导的狼疮样综合征循证诊断与治疗的个案分析[J]. 中国循证医学杂志, 2004, 4(7): 499-502 |
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| 作者姓名： | 杨立川 肖艰 李孜 苏白海 冀玲 刘先蓉 樊均明 |
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| 作者单位： | 四川大学华西医院肾脏内科,成都,610041 |
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| 摘 要： | 狼疮样综合征和抗中性粒细胞胞浆抗体(ANCA)阳性的血管炎合并甲亢在临床中十分罕见.为了找出这三种疾病之间的关系,作者借助循证医学的方法,根据患者病情,提出临床问题,从PubMed(1966～2003年)、中国生物医学文献数据库(CBM)(1978～2003年)、荷兰医学文摘数据库(EMBase)(1974～2003年)查找相关信息.结果发现抗甲状腺药物的副反应是对该病例的最好解释,并据此采取了相应治疗措施,使患者病情获得明显好转.
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| 关 键 词： | 循证医学 抗甲状腺药物副作用 狼疮样综合征 抗中性粒细胞胞浆抗体 |
| 文章编号： | 1672-2531(2004)07-0499-04 |
| 修稿时间： | 2003-11-07 |
Evidence-Based Diagnosis and Treatment of Lupus Erythematosus-Like Syndrome Induced by Anti-Thyroid Drugs |
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| YANG Li-chu an,XI AO Jian,LI Zi,SHU Bai-hai,JI Ling,LIU Xian-rong,FAN Jun-ming. QX) WT"BX. Evidence-Based Diagnosis and Treatment of Lupus Erythematosus-Like Syndrome Induced by Anti-Thyroid Drugs[J]. Chinese Journal of Evidence-based Medicine, 2004, 4(7): 499-502 |
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| Authors: | YANG Li-chu an,XI AO Jian,LI Zi,SHU Bai-hai,JI Ling,LIU Xian-rong,FAN Jun-ming. QX) WT" BX |
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| Affiliation: | YANG Li-chu an,XI AO Jian,LI Zi,SHU Bai-hai,JI Ling,LIU Xian-rong,FAN Jun-ming*. QX) WT5"BX Department of Nephrology,West China Hospital,Sichuan University,Ch engdu 610041,China. |
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| Abstract: | To di agnose and treat a patient with rare lupus erythematosus-like syndrome and anti neutrophil cytoplasmic antibodies (ANCA) positive vasculitis with graves' disea se by applying the approach of evidence-based medicine. Clinical problems were raised based on the patient condition and PubMed (1966-2003), CBM (1978-200 3),EMBASE(1974-2003) were searched for the related information. We found th at the best explaination for this case was antithyroid drugs' side effect, and the patient was obvious better after treatment. JP |
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| Keywords: | Evidence- base d medicine Side effect of antithyroid drugs Lupus erythematosus-like syndrome Antineutrophil cytoplasmic antibodies |
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