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伪膜性肠炎发病机制及诊疗的探讨
引用本文:吕小燕,苏娟萍,冯五金,吕志平,刘改萍. 伪膜性肠炎发病机制及诊疗的探讨[J]. 中国中西医结合消化杂志, 2012, 20(1): 7-9
作者姓名:吕小燕  苏娟萍  冯五金  吕志平  刘改萍
作者单位:1. 山西省中医院脾胃病科,山西太原,030012
2. 南方医科大学中医药学院,广东广州,510515
摘    要:[目的]探讨伪膜性肠炎的发病机制.[方法]结合病史,对1例复发性伪膜性肠炎患者的临床症状、体征,实验室检查和肠镜及其组织病理学进行分析.[结果]以反复腹痛、腹泻为主要临床症状的伪膜性肠炎患者,多次大便培养示肠道菌群失调.[结论]抗生素致肠道菌群失调是引起伪膜性肠炎的主要原因,合理使用抗生素和恢复肠道菌群是伪膜性肠炎的主要治疗手段.

关 键 词:肠炎,伪膜性  菌群失调  抗生素

Study on diagnosis and treatment of pseudomembranous enterocolitis
LV Xiao-yan , SU Juan-ping , FENG Wu-jin , LV Zhi-ping , LIU Gai-ping. Study on diagnosis and treatment of pseudomembranous enterocolitis[J]. Chinese Journal of Integrated Traditional and Western Medicine on Digestion, 2012, 20(1): 7-9
Authors:LV Xiao-yan    SU Juan-ping    FENG Wu-jin    LV Zhi-ping    LIU Gai-ping
Affiliation:1(1Department of Spleen and Stomach Diseases,Shanxi Provincial TCM Hospital, Taiyuan 030012,China;2College of Chinese Medicine,Nanfang Medical University,Guangzhou 510515,China)
Abstract:[Objective]To study the pathogenesis of pseudomembranous enterocolitis.[Methods]Based on the medical record,clinical symptoms,signs,laboratory examination,histopathology and endoscopic images were analyzed in a colon patient who was diagnosed as recurrent pseudomembranous enterocolitis.[Results]Alteration of intestinal flora always existed in the pseudomembranous enterocolitis patient who suffered from repeated abdominal pain and diarrhea.[Conclusion]Antibiotic-associated gastrointestinal microflora disorders may be the main cause of pseudomembranous enterocolitis.Proper application of antibiotics and restoration of the imbalanced flora in the intestine may be the major therapy for pseudomembranous enterocolitis.
Keywords:colits,pseudomembrane  dysbacteriosis  antibiotics
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