| 西酞普兰与阿米替林治疗老年抑郁症对照研究 |
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| 引用本文： | 程平,王天龙,唐鹏,祝家胜.西酞普兰与阿米替林治疗老年抑郁症对照研究[J].中国民康医学,2007,19(11):427-428. |
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| 作者姓名： | 程平 王天龙 唐鹏 祝家胜 |
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| 作者单位： | 湖北咸宁学院精神病学研究所,湖北,咸宁,437100 |
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| 摘 要： | 目的：探讨西酞普兰与阿米替林治疗老年抑郁症的疗效及不良反应。方法：将96例老年抑郁症患者采用随机分组的方法，分为西酞普兰组和阿米替林组，治疗8周采用4级临床疗效及汉密尔顿抑郁量表（HAMA）、汉密尔顿焦虑量表（HAMD）、副反应量表（TESS）评定疗效和不良反应。结果：西酞普兰与阿米替林抗抑郁的疗效相似（P〉0．05），抗焦虑效果优于阿米替林，而且不良反应更轻（P〈0．05）。结论：西酞普兰是一种既有效又安全的新型抗抑郁药，适合对老年抑郁症的治疗。
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| 关 键 词： | 老年抑郁症 西酞普兰 阿米替林 |
| 文章编号： | 0369（2007）06-0427-02 |
| 修稿时间： | 2007-01-29 |
A controlled study on the treatment of senile depression with Citalopram and amitriptyline |
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| CHENG Ping, WANG Tian - long, ZHU Jia - sheng, et al.A controlled study on the treatment of senile depression with Citalopram and amitriptyline[J].medical journal of chinese peoples health,2007,19(11):427-428. |
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| Authors: | CHENG Ping WANG Tian - long ZHU Jia - sheng |
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| Institution: | Psychiatry Institute of Hubei Xianning College, Hubei 437100, China |
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| Abstract: | Objective:To explore the efficacy and side effects of Citalopram and amitriptyline.Methods:96 elderly depressive patients who met CCMD-3 criterion for depression episode were randomly assigned to Citalopram group(n=48) and amitriptyline group(n=48) for the treatment of 8 weeks.The clinical efficacy was evaluated by HAMD and HAMA.The side effects were evaluated by TESS.Results: There was no significant difference of the efficacy between two groups(P>0.05).Citalopram showed rapider efficacy and less side effects than amitriptyline(P<0.05).Conclusions: Citalopram showed observably rapider efficacy in reducing depression and anxiety symptoms and less side effects in treating elderly depression. |
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| Keywords: | Senile depression Citalopram Amitriptyline |
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