Brain ultrasonography findings in neonates with exposure to cocaine during pregnancy |
| |
Authors: | Marian van Huis Anne A. M. W. van Kempen Myrthe Peelen Maaike Timmers Kees Boer Bert J. Smit Rick R. Van Rijn |
| |
Affiliation: | (1) Department of Obstetrics and Gynaecology, Academic Medical Center Amsterdam, Amsterdam, The Netherlands;(2) Department of Paediatrics, Onze Lieve Vrouwe Gasthuis, Amsterdam, The Netherlands;(3) Faculty of Medicine, Academic Medical Center Amsterdam, Amsterdam, The Netherlands;(4) Division of Neonatology, Department of Paediatrics, Erasmus Medical Centre – Sophia Children’s Hospital, Amsterdam, The Netherlands;(5) Department of Radiology, Academic Medical Center Amsterdam, Meibergdreef 9, Amsterdam Zuid-Oost, 1105 AZ, The Netherlands; |
| |
Abstract: | Background Cocaine exposure during pregnancy has been reported to have detrimental effects on the fetus. Objective To describe the findings on cranial ultrasonography (CUS) as part of a neonatal screening programme for exposed neonates. Materials and methods The study was a semiprospective analysis of a 12-year cohort of neonates born to mothers who had used cocaine during their pregnancy and who had follow-up according to a strict clinical protocol. Results In total, 154 neonates (78 boys, 76 girls) were included, of whom 29 (19%) were born preterm, and 125 (81%) were born full-term. Abnormalities on CUS were seen in 37 neonates (24%; 95% CI 18–31%). The abnormalities were classified as minor in 20 (13%; 95% CI 9–19%) and mildly abnormal in 17 (11%; 95% CI 7–17%). None of the infants showed severe abnormalities. The abnormalities were not associated with the duration or maximum amount of cocaine use during pregnancy. Conclusion None of the infants had severe abnormalities. Detected abnormalities were not correlated with the duration or maximum amount of cocaine use. Given these findings, we feel that routine cranial ultrasonography in this population is not warranted. |
| |
Keywords: | Neonate Cocaine Brain Ultrasonography |
本文献已被 SpringerLink 等数据库收录! |
|