| 慢性肾功能衰竭血液透析患者脂蛋白(a)呈高水平状态 |
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| 引用本文： | 王伟灵,刘卫红,宋启发,刘兴晖,彭涛,朱仕荣.慢性肾功能衰竭血液透析患者脂蛋白(a)呈高水平状态[J].华中科技大学学报(医学版),2000,29(2). |
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| 作者姓名： | 王伟灵 刘卫红 宋启发 刘兴晖 彭涛 朱仕荣 |
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| 作者单位： | 1. 东风汽车公司中心医院,检验部,十堰,442008
2. 东风汽车公司中心医院,血液净化中心,十堰,442008 |
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| 摘 要： | 利用免疫比浊法检测 2 1例慢性肾功能衰竭 (CRF)血液透析 (HD)患者透析前后血中脂蛋白 (a) L p(a) ],并同时测定了总胆固醇 (TC) ,甘油三脂 (TG) ,载脂蛋白 A1(Apo A1)和载脂蛋白 B (Apo B)的浓度。结果发现 ,HD患者 L p (a) ,TG,Apo B显著高于正常对照组 (均为 P<0 .0 1) ,HD后无明显改善。提示 HD患者体内存在着 L p (a)等脂代谢紊乱。
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| 关 键 词： | 肾功能衰竭 慢性 脂蛋白(a) 血液透析 |
High Serum Level of Lipoprotein(a) in the Patients with Chronic Renal Failure on Hemodialysis |
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| Abstract: | The lipoprotein(a) Lp(a)] level and the levels of apolipoprotein A1(apoA1)and apolipoprotein B (apoB) in serum were assayed by using immunoturbidimetry in 21 patients with chronic renal failure(CRF) before and after the hemodialysis (HD). At the same time the total cholesterol(TC)and triglyceride(TG)were determined by means of enzymatic method. The results showed that the levels of Lp(a),TG and ApoB were higher in the patients with CRF than those in the normal controls( P <0 01). No obvious improvement was found even after HD. It was suggested that the abnormal lipid metabolism existed in the patients undergoing HD. |
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| Keywords: | renal failure chronic lipoprotein(a) hemodialysis |
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