| Interleukin-1β,Tumor Necrosis Factor-α and Lipopolysaccharide Induce Expression of Monocyte Chemoattractant Protein-1 in Calf Aortic Smooth Muscle Cells |
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| 引用本文： | 孟峰,邓仲端,倪娟.Interleukin-1β,Tumor Necrosis Factor-α and Lipopolysaccharide Induce Expression of Monocyte Chemoattractant Protein-1 in Calf Aortic Smooth Muscle Cells[J].华中科技大学学报(医学英德文版),2000,20(1). |
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| 作者姓名： | 孟峰 邓仲端 倪娟 |
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| 作者单位： | Department of Pathology，School of Basic Medical Sciences，Tongji Medical University，Wuhan 430030 |
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| 基金项目： | This project was supported by a grant from National Natural Science Foundation of China !(No. 39470289). |
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| 摘 要： | The focal influx and accumulation of lipoprotein at arterial lesion--prone sites and the recruitment of blood monocytes to those sites are two early key events in atherogenesis. After entering thesubendothelial space of the arterial wall, monocytes undergo activation--differentiation to becomemacrophages which subsequently internallze oxidatively modified lipoproteins through scavenger receptors and become foam cells. Therefore, tostudy the mechanism of the recruitment of bloodmonocytes to the…
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| 关 键 词： | interleukin-1β tumor necrosis factor α lipopolysaccaride monocyte chemoattractant protein 1 muscle smooth vascular |
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