电针对慢性疲劳综合征病理节律的调整作用

目的：探讨电针对慢性疲劳综合征（CFS）病理节律的调整作用。方法：20例CFS患者与20例健康受试者进行对照，CFS患者采用电针肾俞、足三里进行治疗。应用时间生物学的研究方法对患者治疗前后以及健康受试者进行24h核心体温、心率、血压、唾液皮质醇和褪黑素的动态检测。结果：余弦法分析发现，健康组和CFS组治疗后各项指标都具有昼夜节律（P〈0．05）；CFS组治疗前舒张压昼夜节律消失（P〉0．05），其余指标具有昼夜节律（P〈0．05），但CFS组治疗前昼夜节律振幅低于健康对照组，且核心体温、心率、血压和褪黑素峰值相位后移而皮质醇峰值相位超前；电针治疗后，CFS组振幅明显提高，峰值相位接近于健康对照组（P〉0．05）。结论：CFS存在昼夜节律紊乱现象，电针对其具有良性调整作用。

Adjusting Effects of Electroacupuncture on Pathological Circadian Rhythm of Chronic Fatigue Syndrome

Objective：To probe the adjusting effects of electroacupuncture on the circadian rhythm of patients with chronic fatigue syndrome （CFS）. Methods：The core body temperature, blood pressure, heart rate, cortisol and melatonin of twenty CFS patients and twenty healthy people were estimated with the chronobiologic research method. CFS patients were treated with electroacupuncture at bilateral Shenshu （BL 23） and Zusanli （ST 36）. Results： The circadian indexes of the control group and the CFS group after treatment had their own circadian rhythms （P 〈 0.05）, while the circadian rhythm of the diastolic blood pressure of the CFS group disappeared before the treatment （P〉 0.05）. The circadian rhythm amplitudes of the CFS group were lower than those of the control group before the treatment. The acrophase of the core body temperature, heart rate, blood pressure and melatonin of the CFS group were delayed, while acrophase of cortisol was advanced. The amplitudes were elevated after treatment, and the acrophase could also be positively adjusted to the acrophase of the control group （P〉 0.05）. Conclusion：The CFS patients show an evident disorder of circadian rhythm, and electroacupuncture can adjust the circadian rhythm positively.