| 冠心病患者二甲基精氨酸与颈动脉内膜厚度关系的临床研究 |
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| 引用本文： | 冯薇,曲秀芬,夏伟,宋影.冠心病患者二甲基精氨酸与颈动脉内膜厚度关系的临床研究[J].黑龙江医学,2008,32(12):888-890. |
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| 作者姓名： | 冯薇 曲秀芬 夏伟 宋影 |
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| 作者单位： | 哈尔滨医科大学第一临床医学院心内二科,黑龙江,哈尔滨,150001 |
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| 摘 要： | 目的研究冠心病患者的血清非对称性二甲基精氨酸（ADMA）水平的异常变化与颈动脉内膜厚度的相关性。方法收集2006-06~12间，在我院住院病人58例，分为行冠状动脉造影组（n=29）及正常对照组（n=29）。分别测其血浆中不对称二甲基精氨酸水平、颈动脉内膜-中膜厚度。结果冠脉造影组病人不对称二甲基精氨酸水平明显高于对照组，冠脉造影组病人颈动脉内膜-中膜厚度明显高于对照组，不对称二甲基精氨酸水平与颈动脉内膜-中膜厚度呈正相关。结论提示不对称二甲基精氨酸影响颈动脉内膜-中膜厚度，可能是引起冠状动脉粥样硬化的危险因子。
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| 关 键 词： | 二甲基精氨酸 颈动脉内膜-中膜厚度 冠心病 |
The Relationship Between Asymmetric Dimethylarginine and Intima-media Thickness of the Carotid Artery |
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| FENG Wei,QU Xiu-fen,XIA Wei,et al..The Relationship Between Asymmetric Dimethylarginine and Intima-media Thickness of the Carotid Artery[J].Heilongjiang Medical Journal,2008,32(12):888-890. |
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| Authors: | FENG Wei QU Xiu-fen XIA Wei |
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| Institution: | FENG Wei,QU Xiu-fen,XIA Wei,et al.(The First Clinical Medical College of Harbin Medical University,Harbin 150001,China) |
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| Abstract: | Objective To investigate the relationship between asymmetric dimethylarginine(ADMA) and intima-media thickness of the carotid in the patients of coronary atherosclerosis heart disease.Methods Threety-nine normal volunteers and threety-nine patients with coronary heart disease were enrolled in this study in our hospital from June to December in 2006.The levels of ADMA、intima-media thickness of the carotid artery were evaluated.Results Both of the levels ADMA and intima-media thickness of the carotid artery had a linear correlativity,correlative coefficient closed to 1.Conclusion This study reveals that plasma ADMA levels which decreases intima-media thickness of the carotid may be a marker of coronary atherosclerosis heart disease. |
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| Keywords: | Asymmetric dimethylarginine(ADMA) Intima-media thickness of the carotid artery Coronary atherosclerotic heart disease |
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