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Ph染色体阳性的急性白血病免疫表型及临床特征分析
引用本文:华建媛  杨碧云  石庆芝,杨桂玲.Ph染色体阳性的急性白血病免疫表型及临床特征分析[J].临床血液学杂志,2001,14(1):14-15.
作者姓名:华建媛  杨碧云  石庆芝  杨桂玲
作者单位:华建媛(江西医学院附属第二医院血液科(南昌,330006))       杨碧云(江西医学院附属第二医院血液科(南昌,330006))       石庆芝(江西医学院附属第二医院血液科(南昌,330006))       杨桂玲(江西医学院附属第二医院血液科(南昌,330006))
摘    要:目的探讨Ph染色体阳性的急性白血病(Ph

关 键 词:急性白血病  染色体  免疫表型
文章编号:1004-2806(2001)01-0014-02
修稿时间:2000年3月7日

Immunophenotypic and clinical feature of philadelphia chromosome positive acute leukemia
HUA Jianyuan,YANG Biyun,SHI Qingzhi,YANG Guilin.Immunophenotypic and clinical feature of philadelphia chromosome positive acute leukemia[J].Journal of Clinical Hematology,2001,14(1):14-15.
Authors:HUA Jianyuan  YANG Biyun  SHI Qingzhi  YANG Guilin
Institution:HUA Jianyuan 1 YANG Biyun 1 SHI Qingzhi 1 YANG Guilin 1
Abstract:Objective:To explore the immunophenotypic and clinical features of philadelphia chromosome posetive acute leukemia (Ph +AL).Methods:Nineteen previously untreated Ph +AL were included,Morphologic/Cytogenetic and immunophenotypic examinations were performed.Results:19 cases were characteristic of Ph +(ALL 9 cases,AML 10 cases).The incidence in ALL was 33.3 %,in AML was 9.3 %.The incidence of CD 10 was 80.0 % in Ph +ALL expressed B lineage antigen.Lyymphocyte lineage antigen expression was high in Ph +AML and it related with M 5.CR rate in Ph +ALL was 66.7 %,in Ph +AML was 30%.Conclusions:Patients of Ph +AL were particularity with immunphenotypic and clinical features,it had a characteristic of worse curative effect and shortter DFS.
Keywords:Leukemia  Acute Philadelphia  Chromosome  Immunophenotype
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