TACE＋PEI治疗原发性肝癌的临床研究

目的探讨肝动脉化疗栓塞术（TACE）结合经皮肝穿刺无水酒精注射术（PEI）治疗原发性肝癌的临床疗效。方法将82例肝癌患者分为对照组和治疗组，对照组单纯行TACE治疗，治疗组给予TACE＋PEI治疗，比较两组的治疗效果。结果治疗组与对照组相比，AFP下降率为88．2％和42．5％，肿瘤体积缩小有效率为83．5％和45％。半年、1年、2年生存率分别为100％、78．04％、53．65％和73．17％、52．22％、24．39％，差异有统计学意义（P〈0．05）。结论肝动脉化疗栓塞术（TACE）结合经皮肝穿刺无水酒精注射术（PEI）治疗原发性肝癌的临床疗效明显优于单纯肝动脉化疗栓塞组。

Clinical research of treatment with TACE combine PEI in hepatocellular carcinoma

Objective To investigate Transarterial chemoembolization(TACE)combine percutancous ethanol injection(PEI)in the treatment of hepatocellular carcinoma(HCC).Methods We divided 82 proven cases of hepatocellular carcinoma into two groups.therapy group were treated by TACE+PEI,control group were treated by TACE.Results For patients in therapy group,AFP declined rate was 88.2%,the volume of phyma minifled 83.5%,the 0.5,1 and 2 year of survival rates were 100.0%,78.04%,53.65%.For control group,AFP declined rate was 42.5%,the volume of phyma minified 45.0%,the 0.5,1,2 year of survival rates were 73.17%,52.22%,24.39%.AFP declined rate,minification of phyma volume and Survival rate in the therapy group was significantly different between therapy groupand control group(P<0.05).Conclusion TACE+PEI can significantly increase survival rate in patients with hepatocelluar carcinoma.It,s therapeutic effect is better than treated by TACE.