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奥拉西坦联合尼莫地平治疗血管性痴呆的疗效观察
引用本文:梁雁,吴泳,梁汉周.奥拉西坦联合尼莫地平治疗血管性痴呆的疗效观察[J].中国实用医药,2010,5(15):45-46.
作者姓名:梁雁  吴泳  梁汉周
作者单位:1. 广东省高州市人民医院神经内科,525200
2. 广东省高州市人民医院脑血管内科,525200
摘    要:目的观察奥拉西坦联合尼莫地平治疗血管性痴呆的临床疗效。方法将150例血管性痴呆患者随机分为3组,分别接受奥拉西坦治疗、尼莫地平治疗、奥拉西坦和尼莫地平联合治疗。治疗前后均运用简易智力状态检查量表(MMSE)积分法进行评价。结果 3周后奥拉西坦治疗组总有效率82.0%,联合治疗组总有效率92.0%,明显高于尼莫地平治疗组,各组治疗前后MMSE积分的变化有显著性差异(P〈0.05),而联合用药组总有效率最高,MMSE积分的变化最明显,同时不良反应无明显增加。结论奥拉西坦是治疗血管性痴呆的有效药物之一,尼莫地平治疗对血管性痴呆也有一定的效果,两者联合使用能显著改善血管性痴呆患者的MMSE评分,临床疗效确切、安全。

关 键 词:血管性痴呆  奥拉西坦  尼莫地平  联合  简易智力状态检查量表

The observation of curative effect of Oxiracetam Injection combined with Nimodipine Tablets in treating the Vascular Dementiame
LIANG Yan,WU Yong,Liang Han Zhou.The observation of curative effect of Oxiracetam Injection combined with Nimodipine Tablets in treating the Vascular Dementiame[J].China Practical Medical,2010,5(15):45-46.
Authors:LIANG Yan  WU Yong  Liang Han Zhou
Institution:(Department of internal neurology, People’s hospital of Gaozhou county of Guangdong province, Guangzhou 525200, China )
Abstract:Objective To observe the curative effect of Oxiracetam Injection combined with Nimodipine Tablets in treating the Vascular Dementiame.Methods 150 cases with Vascular Dementiame, were randomly assigned to 3 groups: Oxiracetam Injection group,Nimodipine Tablets group,Oxiracetam Injection combined with Nimodipine Tablets group.The MMSE scores were graded before and after treatment.Results After 3 weeks,the total effective rate of Oxiracetam Injection group and the total effective rate of Oxiracetam Injection c...
Keywords:Vascular Dementiame  Oxiracetam Injection  Nimodipine Tablets  combination  MMSE  
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