| 乏氧诱导因子-1和肿瘤放射敏感性 |
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| 引用本文： | 陆雪官,冯炎. 乏氧诱导因子-1和肿瘤放射敏感性[J]. 国际肿瘤学杂志, 2007, 34(8): 589-592 |
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| 作者姓名： | 陆雪官 冯炎 |
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| 作者单位： | 苏州大学附属第二医院放射治疗科,215004 |
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| 摘 要： | 研究表明肿瘤微环境乏氧能引起肿瘤放疗抗拒性的增加,而在此过程中乏氧诱导因子-1 （HIF-1）起着关键的作用。这为研究和应用针对HIF-1的分子靶向治疗以提高肿瘤放射敏感性提供了一条有效的途径。
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| 关 键 词： | 肿瘤 放射疗法 乏氧诱导因子-1 |
| 文章编号： | 1673-422X（2007）08-0589-04 |
| 修稿时间： | 2007-03-14 |
Hypoxia inducible factor-1 and tumor radiosensitivity |
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| LU Xue- guan. Hypoxia inducible factor-1 and tumor radiosensitivity[J]. Journal of International Oncology, 2007, 34(8): 589-592 |
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| Authors: | LU Xue- guan |
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| Affiliation: | Department of Radiation Oncology, the Second Affiliated Hosptial of Soochow University, Suzhou 215004, China |
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| Abstract: | It is considered that hypoxia reduces tumor radiosensitivity and hypoxia-inducible factor-1 plays an important role in this process. This gives us a promising molecular therapy targeted to hypoxia inducible factor-1 to enhance the tumor radiosensitivity. |
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| Keywords: | Neoplasms Radiotherapy Hypoxia inducible factor-1 |
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