Parsley: a review of ethnopharmacology,phytochemistry and biological activities |
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Authors: | Mohammad Hosein Farzaei Zahra Abbasabadi Mohammad Reza Shams Ardekani Roja Rahimi Fatemeh Farzaei |
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Affiliation: | 1. Faculty of Pharmacy, Kermanshah University of Medical Science, Kermanshah 6734667149, Iran;2. Department of Traditional Pharmacy, Faculty of Traditional Medicine, Tehran University of Medical Science, Tehran 1417653761, Iran;3. Faculty of Pharmacy, Kermanshah University of Medical Science, Kermanshah 6734667149, Iran;4. Department of Traditional Pharmacy, Faculty of Traditional Medicine, Tehran University of Medical Science, Tehran 1417653761, Iran;5. Department of Pharmacognosy, Faculty of Pharmacy, Tehran University of Medical Science, Tehran 1417653761, Iran;6. Department of Traditional Pharmacy, Faculty of Traditional Medicine, Tehran University of Medical Science, Tehran 1417653761, Iran;g College of Veterinary Medicine, Kermanshah Razi University, Kermanshah 6715685414, Iran |
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Abstract: | ObjectiveTo summarize comprehensive information concerning ethnomedicinal uses, phytochemistry, and pharmacological activities of parsley.MethodsDatabases including PubMed, Scopus, Google Scholar, and Web of Science were searched for studies focusing on the ethnomedicinal use, phytochemical compounds and biological and pharmacological activities of parsley. Data were collected from 1966 to 2013. The search terms were: “Parsley” or “Petroselinum crispum” or “Petroselinum hortence”.ResultsParsley has been used as carminative, gastro tonic, diuretic, antiseptic of urinary tract, anti-urolithiasis, anti-dote and anti-inflammatory and for the treatment of amenorrhea, dysmenorrhea, gastrointestinal disorder, hypertension, cardiac disease, urinary disease, otitis, sniffle, diabetes and also various dermal disease in traditional and folklore medicines. Phenolic compounds and flavonoids particularly apigenin, apiin and 6″-Acetylapiin; essential oil mainly myristicin and apiol; and also coumarins are the active compounds identified in Petroselinum crispum. Wide range of pharmacological activity including antioxidant, hepatoprotective, brain protective, anti-diabetic, analgesic, spasmolytic, immunosuppressant, anti-platelet, gastroprotective, cytoprotective, laxative, estrogenic, diuretic, hypotensive, antibacterial and antifungal activities have been exhibited for this plant in modern medicine.ConclusionIt is expectant that this study resulted in improvement the tendencies toward Petroselinum crispum as a useful and important medicinal plant with wide range of proven medicinal activity. |
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Keywords: | Petroselinum Jafari Medicine, traditional Pharmacological processes Chemistry |
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