Curative effect of heat-sensitive moxibustion on chronic persistent asthma: a multicenter randomized controlled trial |
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| Authors: | Rixin Chen Mingren Chen Jun Xiong Zhenhai Chi Bo Zhang Ning Tian Zhenhua Xu Tangfa Zhang Wanyao Li Wei Zhang Xiaofeng Rong Zhen Wang Gang Sun Baohe Ge Guoxiong Yu Nanchang Song |
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| Affiliation: | 1. Department of Acupuncture and Rehabilitation, Hospital Affiliated to Jiangxi University of Traditional Chinese Medicine, Nanchang 330006, China;2. Department of Rehabilitation, Guangdong Hospital of Combination of Traditional Chinese Medicine with Western Medicine, Foshan 528000, China;3. Department of Pneumology, Guangdong Hospital of Traditional Chinese Medicine, Guangzhou 519015, China;4. Department of Acupuncture, First Hospital of Wuhan, Wuhan 430032, China;5. Institute of Acupuncture and Massage, Guangzhou University of Traditional Chinese Medicine, Guangzhou 510405, China;6. Department of Pneumology, First Hospital Affiliated to Nanchang University, Nanchang 330006, China;g Department of Rehabilitation, First Hospital Affiliated to Chongqing Medical University, Chongqing 400016, China;h Department of Acupuncture, First Hospital Affiliated to Zhejiang University of Traditional Chinese Medicine, Hangzhou 310018, China;i Department of Acupuncture, Suzhou Hospital of TCM, Suzhou 215003, China;j Department of Acupuncture, Hospital Affiliated to Shandong University of Traditional Chinese Medicine, Jinan 250011, China;k Department of Acupuncture, Guangdong Disabled Soldier Hospital, Guangzhou 510260, China;l Department of Acupuncture, Nanchang Hospital of combination of Traditional Chinese Medicine with Western Medicine, Nanchang 330003, China |
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| Abstract: | ObjectiveTo compare the curative effects of heat-sensitive moxibustion with conventional drugs on chronic persistent asthma and seek a valuable therapy to replace Western Medicine.MethodsThe participants in this multi-center, randomized, and controlled study were randomly divided into two groups: group A (n=144), treated with heat-sensitive moxibustion (50 sessions) and group B (n=144), treated with Seretide (salmeterol 50 µg/fluticasone 250 µg, twice a day). The scores of asthma control test (ACT), forced expiratory volume in 1 second (FEV1), peak expiratory flow (PEF), and attack frequency were measured after 15, 30, 60, and 90 days of treatment. Patients followed up 3 and 6 months after treatment.ResultsThere was a significant difference (P= 0.0002) in the ACT score and lung function between the two groups after 3 months of treatment and (P=0.000 03) during the follow-up visits. In addition, heat-sensitive moxibustion reduced attack frequency in the period from inclusion to the 6-month follow-up visit.ConclusionThis study shows that heat-sensitive moxibustion may have a comparable curative effect to Seretide(salmeterol/fluticasone) on asthma. |
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| Keywords: | Moxibustion Asthma Randomized controlled trial Heat sensitive Seretide |
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