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ATP-Binding Cassette Transporter G2 Mediates the Efflux of Phototoxins on the Luminal Membrane of Retinal Capillary Endothelial Cells
Authors:Tomoko Asashima  Satoko Hori  Sumio Ohtsuki  Masanori Tachikawa  Masahiko Watanabe  Chisato Mukai  Shinji Kitagaki  Naoki Miyakoshi  Tetsuya Terasaki
Institution:(1) Department of Molecular Biopharmacy and Genetics, Graduate School of Pharmaceutical Sciences, Tohoku University, Aoba, Aramaki, Aoba-ku, Sendai 980-8578, Japan;(2) New Industry Creation Hatchery Center, Tohoku University, Aoba, Aramaki, Aoba-ku, Sendai 980-8579, Japan;(3) CREST and SORST of Japan Science and Technology Agency (JST), , Japan;(4) Department of Anatomy, Hokkaido University School of Medicine, Sapporo 060-8638, Japan;(5) Division of Pharmaceutical Sciences, Graduate School of Natural Science and Technology, Kanazawa University, Kakuma-machi, Kanazawa 920-1192, Japan
Abstract:
Keywords:ABC half-transporter  ABCG2/BCRP/MXR/ABCP  inner blood–  retinal barrier  pheophorbide a  retinal capillary endothelial cell
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