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Oseltamivir-resistant pandemic (H1N1) 2009 virus, South Korea |
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| Authors: | Yi Hwajung Lee Joo Yeon Hong Eun Hye Kim Mi Seon Kwon Donghyok Choi Jang Hoon Choi Woo Young Kim Ki Soon Lee Jong Koo Oh Hee Bok Kang Chun |
| Affiliation: | Korea Centers for Disease Control and Prevention, Seoul, South Korea. |
| Abstract: | To identify oseltamivir resistance, we analyzed neuraminidase H275Y mutations in samples from 10 patients infected with pandemic (H1N1) 2009 virus in South Korea who had influenza that was refractory to antiviral treatment with this drug. A neuraminidase I117M mutation that might influence oseltamivir susceptibility was detected in sequential specimens from 1 patient. |
| Keywords: | Influenza antiviral resistance oseltamivir neuraminidase hemagglutinin pandemic H1N1 viruses CME dispatch |
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