动态血糖监测系统对HbA1c<6.5%的2型糖尿病患者无症状低血糖事件的评估价值

目的:评价动态血糖监测系统(CGMS)对糖化血红蛋白(HbA1c)<6.5%的2型糖尿病(T2DM)患者胰岛素治疗中无症状低血糖事件的重要意义。方法:将87例使用胰岛素治疗的HbA1c<6.5%的T2DM患者随机分成CGMS组和自我血糖监测(SMBG)组。CGMS组进行连续72 h血糖监测,SMBG组每天监测8次毛细血糖,共3 d。比较两种监测方法对低血糖,尤其是无症状低血糖的检出率。结果:SMBG组患者监测3 d发现12例出现16次低血糖,其中4例无症状低血糖5次;CGMS监测72 h发现29例出现108次低血糖,其中23例无症状低血糖65次,以夜间多见,66.7%见于病程超过10年的患者。结论:CGMS在HbA1c<6.5%的T2DM患者胰岛素治疗中可作为监测低血糖尤其是无症状低血糖的较好方法。

Clinical significance of the continuous glucose monitoring on asymptomatic hypoglycaemia reaction in type 2 diabetes mellitus patients with HbA1c<6.5%

Objective:To evaluate the continuous glucose monitoring on hypoglycaemia reaction in type 2 diabetes mellitus patients(T2DM)with HbA1c<6.5%.Methods:Eighty-seven patients of T2DM with HbA1c<6.5% undergoing insulin intensification therapy were randomly divided into continuous glucose monitoring system(CGMS) group and self-monitoring of blood glucose(SMBG) group.The blood glucose levels of the CGMS group were monitored continuously using CGMS for 72 hours.The blood glucose levels of the SMBG group were monitor...