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INFLUENCE OF NUTRITIONAL STATUS ON PHARMACOKINETICS OF CONTRACEPTIVE PROGESTOGENS
Abstract:Malnutrition enhances the metabolic clearance of oral progestogens in women and experimental rabbits. This appears to be due to increased drug metabolizing enzyme activities and uterine-progesterone-receptor concentration.
Keywords:contraceptive progestogens    pharmacokinetics in women    rabbits    body weight effect    microsomal drug metabolizing enzymes    progesterone receptors
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