经导管肝动脉化疗栓塞联合CT引导下经皮乙酸注射治疗原发性巨块型肝癌的疗效分析

目的探讨经导管肝动脉化疗栓塞（TACE）联合CT引导下经皮乙酸注射（PAI）治疗巨块型肝癌的临床应用价值。方法43例原发性巨块型肝癌患者随机分为两组，对A组21例行常规TACE治疗，于首次TACE治疗后，每间隔1个月重复治疗1次，共3次为一疗程；对B组22例行TACE联合PAI治疗，于首次TACE后2～3周在CT引导下行PAI治疗，每周1次，共6～9次为一个疗程。随访两组患者生存情况，并监测血清AFP，观察疗效。随访过程中若肿瘤复发，重复上述治疗一个疗程。结果治疗完成后1个月，两组AFP阳性率差异无统计学意义；单纯TACE、TAcE＋PAI治疗有效率分别为38．10％和77．27％，差异有统计学意义。A组1、2、3年生存率分别为47．62％、23．81％、9．52％，B组分别为81.82％、54．55％、36．36％，差异均有统计学意义。结论TACE联合PAI治疗巨块型肝癌疗效优于单纯TACE。

Efficiency analysis of transcatheter arterial chemoembolization combined with CT-guided percutaneous acetic acid injection for huge hepatocellular carcinoma

Objective To explore the clinical application value of transcatheter arterial chemoembolization(TACE) combined with CT-guided percutaneous acetic acid injection(PAI) in treatment of huge hepatocellular carcinoma(HCC).Methods Forty-three patients with huge HCC were randomly divided into two group.Twenty-one patients in group A underwent routine one course for TACE(three times),and the interval of TACEs was one month.Twenty-two patients in group B underwent TACE combined with PAI,and CT-guided PAI was perform...