| 制备N－2，6－二氯苯胺的新工艺路线研究 |
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| 引用本文： | 李洪涛,郭嘉林,姜兆竞,郑文义,计志忠. 制备N－2，6－二氯苯胺的新工艺路线研究[J]. 中国药物化学杂志, 1995, 0(3) |
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| 作者姓名： | 李洪涛 郭嘉林 姜兆竞 郑文义 计志忠 |
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| 作者单位： | 沈阳药科大学药物研究所 |
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| 摘 要： | 以环己酮为起始原料经２，２，６，６－四氯环己酮制备Ｎ－苯基－２，６－二氯苯胺（双氯灭痛的中间体）的新工艺路线。工艺简单、产品质量好、＂三废＂少，可较大幅度降低成本。
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| 关 键 词： | 2．2．6．6－四氯环己酮；N－苯基－2．6－二氯苯胺；双氯灭痛 |
Studies on The New Preparation of N-Phenyl-2,6-Dichloroaniline |
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| Li Hongtao,Guo Jialin ,Jiang Zaojing,Zheng Wenyi,Ji Zhizhong. Studies on The New Preparation of N-Phenyl-2,6-Dichloroaniline[J]. Chinese Journal of Medicinal Chemistry, 1995, 0(3) |
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| Authors: | Li Hongtao Guo Jialin Jiang Zaojing Zheng Wenyi Ji Zhizhong |
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| Abstract: | The new process, by which N-phenyl 2,6-dichloronailine is prepared(an intermidiate for preparing dichlofenac sodium)from the starting material cyclonexanone through 2,2,6,6-tetrachlorocyclo-hexanone, is comparablely simple, with better quality of the product,less wastes and much lower costs. |
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| Keywords: | Tetrachloroeyclohexanone Dichlofenac sodium N-phenyl 2 6-dichloronailine |
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