| 枸地氯雷他定联合玉屏风颗粒治疗慢性荨麻疹疗效观察 |
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| 引用本文： | 赵春华,金艺,钱晓莺,周宇.枸地氯雷他定联合玉屏风颗粒治疗慢性荨麻疹疗效观察[J].上海中医药杂志,2017,51(9):74-77. |
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| 作者姓名： | 赵春华 金艺 钱晓莺 周宇 |
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| 作者单位： | 浙江省荣军医院皮肤科,浙江嘉兴,314000,浙江省嘉兴市妇幼保健院皮肤科,浙江嘉兴,314000,浙江省荣军医院皮肤科,浙江嘉兴,314000,浙江省荣军医院皮肤科,浙江嘉兴,314000 |
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| 摘 要： | 目的观察枸地氯雷他定联合玉屏风颗粒治疗慢性荨麻疹(CU)临床效果。方法将86例CU患者根据随机数字表法分为对照组和治疗组,每组43例。对照组予枸地氯雷他定口服,治疗组在此基础上予玉屏风颗粒口服,均治疗4周。观察临床疗效,荨麻疹活动度评分(UAS)评估病情严重程度,皮肤病生活质量指标评分(DLQI)评估生活质量,检测血清白介素-4(IL-4)、干扰素-γ(IFN-γ)、免疫球蛋白E(Ig E)变化。结果 (1)对照组总有效率为72.09%,治疗组为90.70%;治疗组疗效明显优于对照组(P0.05)。(2)治疗后,两组瘙痒、风团症状评分均降低(P0.01),且治疗组低于对照组(P0.01)。(3)治疗后,两组生活质量评分均显著降低(P0.01),且治疗组低于对照组(P0.01)。(4)治疗后,两组IL-4、Ig E均降低(P0.05),IFN-γ升高(P0.05),且治疗组改善优于对照组(P0.05)。结论枸地氯雷他定联合玉屏风颗粒治疗慢性荨麻疹临床疗效确切,可提高患者生活质量、改善其免疫状态。
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| 关 键 词： | 荨麻疹 枸地氯雷他定 玉屏风颗粒 IgE |
| 收稿时间： | 2017/4/20 0:00:00 |
Efficacy observation of desloratadine citrate disodium combined with Yupingfeng Granule in the treatment of chronic urticaria |
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| ZHAO Chun-hu,JIN Yi,QIAN Xiao-ying and ZHOU Yu.Efficacy observation of desloratadine citrate disodium combined with Yupingfeng Granule in the treatment of chronic urticaria[J].Shanghai Journal of Traditional Chinese Medicine,2017,51(9):74-77. |
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| Authors: | ZHAO Chun-hu JIN Yi QIAN Xiao-ying and ZHOU Yu |
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| Institution: | Department of Dermatology,Zhejiang Rongjun Hospital,Jiaxing,Zhejiang,314000,Department of Dermatology,Jiaxing Maternity and Child Health Care Hospital,Jiaxing,Zhejiang,314000,Department of Dermatology,Zhejiang Rongjun Hospital,Jiaxing,Zhejiang,314000 and Department of Dermatology,Zhejiang Rongjun Hospital,Jiaxing,Zhejiang,314000 |
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