青蒿素类化合物专利格局分析

目的：青蒿素及其系列衍生物的抗疟作用已被广泛认可，该类化合物的其他生物活性也受到广泛关注，深入的实验研究产生了大量专利文献。本文对青蒿素、青蒿酸和青蒿乙素的专利申报情况进行了系统梳理，以展示其研发态势，为规划研究路线、制订专利申请策略提供参考。方法：制订检索策略，从多个专利数据库检索和下载题录信息，利用统计学软件对题录中的有效信息进行分析挖掘。结果：获得了青蒿素类化合物专利申请的生命周期、应用功效偏好、优秀申请机构和高价值专利等方面的格局情报。结论：该领域专利技术生命周期整体处于技术成熟期。其中，青蒿素发展空间相对较大，最受关注的应用功效包括抗寄生虫、抗肿瘤和抗感染，而内部引用的核心主题是治疗皮肤病、抑制癌症。

Patent Map of Artemisinin Derivatives

The antimalarial activity of artemisinin and its derivatives have been widely recognized. A deep scientificresearch had produced many patent documents. In order to formulate strategies on research and patent application rationally, it is necessary to carry an analysis existing patent application systematically. Necessary patent bibliographicinformation was searched and downloaded using professional patent database. And then, patent and industrial patternwithin were extracted comprehensively. Main subjects included artemisinin, artemisinic acid and arteannuin B. Theresults showed that through a series of statistical analysis, information on life cycle of artemisinin patent applications,application efficiency preferences, excellent applications and high value patents was obtained. It was concluded that inthis field, the patent technology life cycle is in mature stage. Among them, artemisinin has a relatively large space fordevelopment. The most popular applications are anti-parasite, anti-tumor and anti-infection. The core theme of internalreference is to treat skin diseases and to suppress cancer.