HIV/HCV合并感染者中两类抗病毒药物相互作用的研究

直接抗病毒药物对HIV/HCV合并感染者及单纯HCV感染者的疗效相当,然而药物-药物相互作用是临床医师在选择抗病毒方案时不容忽视的问题.本文检索分析了国内外有关直接抗病毒药物与抗反转录病毒药物相互作用的文献,并对两类抗病毒药物的相互作用进行综述,以期为临床医师治疗HIV/HCV合并感染者时选择恰当的直接抗病毒药物组合提供参考.

Research of drug-drug interactions between 2 antiviral agents in HIV/HCV co-infected patients

HIV/HCV co-infected patients shar the same treatment rate as HCV-monoinfected individuals with the use of directly acting antiviral. But we should pay attention to drug-drug interactions in formulating treatment scheme. Drug-drug interactions between antiretrovirals and directly acting antiviral are summarized in this paper through retrieving domestic and foreign literatures, in the hope of providing the reference for the choice of antivirus therapy for HIV/HCV co-infected patients.