亚肺叶切除术治疗早期非小细胞肺癌的研究进展

在过去的五十年里,早期非小细胞甚至是微小肺癌的标准手术方式一直都是肺叶切除加淋巴结清扫,而亚肺叶切除则被认为是高龄患者、严重肺部疾病患者以及其他严重伴随疾病的高风险肺癌患者的妥协性手术。近年来,由于临床CT扫描的广泛应用,更多早期肺癌,尤其是以磨玻璃结节(Ground Glass Opacit,GGO)为主的"惰性"肺癌被发现,且由于人口老龄化所致的老年肺癌患者以及多原发病灶的肺癌患者逐渐增多,亚肺叶切除又重新受到了重视。然而,亚肺叶切除对"小节结"肺癌患者或是影像学表现为GGO的肺癌患者,其手术是否充分还有待于进一步研究。如果亚肺叶切除保留了足够的肺功能,且达到或接近肺叶切除的肿瘤学预后,亚肺叶切除则可跻身早期非小细胞肺癌治疗方式的第一阵容。

Advances in the treatment of early non - small cell lung cancer by Sublobar resection

In the past fifty years, the early non-small cell even tiny the standard operation for lung cancer has been a lobectomy plus lymph node cleaning, while the Sublobar resection is considered to be older patients, patients with severe lung disease, high-risk patients with lung cancer and other serious diseases proneness to surgery. In recent years, due to the widespread use of clinical CT scans, more early lung cancer, especially ground-glass opacity (GGO) -based "inert" lung cancer was found, and due to population aging caused by elderly patients with lung cancer As well as multiple primary lesions of lung cancer patients gradually increased, Sublobar resection has been new attention. However, Sublobar resection for small lung cancer patients or lung cancer patients with radiographic nodules (GGO), whether the operation is sufficient to be further studied. If the Sublobar resection retains sufficient lung function, and has reached or close to the lobectomy of the oncology prognosis, Sublobar resection can be placed in early non-small cell lung cancer treatment of the first team.