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延胡索化学成分、药理活性及毒副作用研究进展
引用本文:何晓凤,张晶,张梅.延胡索化学成分、药理活性及毒副作用研究进展[J].上海中医药杂志,2017,51(11):97-100.
作者姓名:何晓凤  张晶  张梅
作者单位:吉林农业大学中药材学院,吉林长春,130118,吉林农业大学中药材学院,吉林长春,130118,吉林修正药业高新制药有限公司,吉林长春,130103
基金项目:吉林省科技发展项目(20160204004YY)
摘    要:综述延胡索的化学成分、药理活性和毒副作用的研究现状。目前从延胡索中分离并鉴定出40多种生物碱和大量非生物碱类物质;延胡索除具有镇痛、镇静、抗血栓药理活性外,还具有抗肿瘤、抗糖尿病及糖尿病并发症、提高机体抗应激能力等活性。

关 键 词:延胡索  化学成分  药理活性  毒副作用  综述
收稿时间:2017/2/20 0:00:00

Research progress on chemical constituents,pharmacological activities and toxic side effects of Rhizoma Corydalis
HE Xiao-feng,ZHANG Jing and ZHANG Mei.Research progress on chemical constituents,pharmacological activities and toxic side effects of Rhizoma Corydalis[J].Shanghai Journal of Traditional Chinese Medicine,2017,51(11):97-100.
Authors:HE Xiao-feng  ZHANG Jing and ZHANG Mei
Institution:College of Chinese Medicinal Materials,Jilin Agriculture University,Changchun,130118,College of Chinese Medicinal Materials,Jilin Agriculture University,Changchun,130118 and Gaoxin Pharmaceutical Co., Let, Jilin Xiuzheng Pharmaceutical Group, Changchun, 130103
Abstract:This paper reviews the research status of chemical constituents,pharmacological activities and toxic side effects of Rhizoma Corydalis. At present,more than 40 kinds of alkaloids as well as a large number of non-alkaloid substances have been separated and identified from Rhizoma Corydalis. Except the analgesic,sedative and antithrombotic effects,it also shows the pharmacological activities such as anti-tumor,anti-diabetes and diabetic complications,improving the body resistance to stress. With the widespread application of Rhizoma Corydalis,there are a few studies on its toxic side effects.
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