Structural changes in spiny neurons of the rat striatum after a unilateral injection of 6-hydroxydopamine

A decrease in the profile field of bodies and dendrite branching of neurons is revealed. An increase in dendrite lengths and in the area occupied by the bodies of spiny neurons is demonstrated 4 and 12 months postoperation due to the growth of terminal dendritic segments and increased number and length of unbranched dendrites. The positive changes in striatal spiny neurons after injection of 6-hydroxydopamine are indicative of a high level of their plasticity. Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol, 117, N ^o 4, pp. 446–448, April, 1994 Presented by O. S. Adrianov, Member of the Russian Academy of Medical Sciences