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2005-2010年郑州市腹泻病患者志贺病原菌检测
引用本文:程春荣,李伟,田宏茹,赵慧霞,安戈,罗琦,刘战伟. 2005-2010年郑州市腹泻病患者志贺病原菌检测[J]. 河南医学研究, 2012, 21(2): 225-227
作者姓名:程春荣  李伟  田宏茹  赵慧霞  安戈  罗琦  刘战伟
作者单位:1. 郑州市疾病预防控制中心 河南郑州450007
2. 郑州市第二人民医院 河南郑州450000
3. 郑州市二七区妇幼保健所 河南郑州450052
4. 范县疾病预防控制中心 河南范县457000
基金项目:国家十一五科技重大专项课题资助项目
摘    要:目的:了解郑州市2005年至2010年志贺菌血清型别的变化。方法:依照《痢疾防治手册》开展志贺菌实验室检测。结果:共监测腹泻病患者2851例,检出志贺菌183株(6.42%),其中福氏菌145株(79.2%);宋内菌38株(占20.8%)。145株福氏菌中,F4c亚型55株(30.0%),F2a亚型39株(21.3%),F1a亚型36株(19.7%),F2b亚型6株(3.3%),Fx变种4株(2.2%),F4a亚型2株(1.1%),Fy变种1株(0.5%),F1b亚型1株(0.5%),F6亚型1株(0.5%);宋内Ⅰ型30株(16.4%),宋内Ⅱ型8株(4.4%)。结论:F4c亚型志贺菌为本市2005年和2006年菌株流行的优势菌株,2007至2010年逐渐被F2a亚型和宋内菌相取代。

关 键 词:志贺菌  优势菌株  腹泻病患者

Detection for Shigella from diarrhea cases in Zhengzhou city from 2005 to 2010
CHENG Chun-rong , LI Wei , TIAN Hong-ru , ZHAO Hui-xia , AN Ge , LUO Qi , LIU Zhan-wei. Detection for Shigella from diarrhea cases in Zhengzhou city from 2005 to 2010[J]. Henan Medical Research, 2012, 21(2): 225-227
Authors:CHENG Chun-rong    LI Wei    TIAN Hong-ru    ZHAO Hui-xia    AN Ge    LUO Qi    LIU Zhan-wei
Affiliation:1.Zhengzhou Center for Diseases Control and Prevention,ZhengZhou 450053,China;2.Second People’s Hospital of Zhengzhou City,ZhengZhou 450000,China;3.Two Seven Area of Zhengzhou City by the Maternal and Child Health,Zhengzhou 450052,China;4.Fanxian Center for Diseases Control and Prevention,Fanxian 457000,China)
Abstract:Objective: To investigate the serotype distribution of Shigellosis Zhengzhou city from 2005 to 2010. Methods: According to the Project for Surveillance of Shigellosis in Chinato carry out shigella bacteria laboratory testing. Results: 183 strains of shigella were isolated from 2851 diarrhea cases(6.65%).Among them,145 strains were S.flexneri(145/183,79.2%) and 38 strains were S.sonnei(38/183,20.8%).Among the 145 strains of S.flexneri,55 subtype were F4c(30.0%),39 subtype were F2a(21.3%),36 subtype were F1a(19.7%),6 subtype were F2b(3.3%),4 subtype were Fx(2.2%),2 subtype were F4a(1.1%),1 subtype were Fy(0.5%) and 1 strains were F6(0.5%).Among the 38 strains of S.sonnei,30 strains were SⅠ.sonnei(16.4%) and 8 strains were SⅡ.sonnei(4.4%). Conclusion: F4c was the major prevalence subtype(2005 and 2006),F2a and S.sonnei was the major prevalence subtype and serotype(2007-2010).
Keywords:shigella spp  major prevalence serotype  diarrhea cases
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