首页 | 本学科首页   官方微博 | 高级检索  
     

2型糖尿病合并感染患者胰岛素泵与胰岛素多点注射的比较研究
引用本文:马建华,吴锦丹,徐小华,付丽媛,李惠琴,孙睿,沈赟,任轶飞,毛晓明,齐绍康. 2型糖尿病合并感染患者胰岛素泵与胰岛素多点注射的比较研究[J]. 医学研究生学报, 2007, 20(12): 1260-1262
作者姓名:马建华  吴锦丹  徐小华  付丽媛  李惠琴  孙睿  沈赟  任轶飞  毛晓明  齐绍康
作者单位:南京医科大学附属南京第一医院内分泌科,江苏南京,210012
摘    要:目的比较持续皮下胰岛素注射(CSII)和多次皮下胰岛素注射(MDI)在合并感染的2型糖尿病(T2DM)患者中的应用.方法合并感染的T2DM患者,CSII组157例,MDI组150例,均进行短期胰岛素强化治疗,对两组血糖水平、血糖漂移幅度、血糖达标时间、单位体质量的胰岛素用量和低血糖发生率等进行比较.结果CSII组血糖达标时间为(6.73±2.73)d,MDI组为(7.51±2.38)d(P<0.05);血糖稳定于靶目标值的比例CSII组比MDI高(P<0.05);且达标时胰岛素用量CSII组偏低(P<0.05);两组前5天的治疗比较,CSII组总体血糖水平低(P<0.05),单位体质量的胰岛素用量较少(P<0.05);两组低血糖的发生率无显著性差异.结论在T2DM患者中用CSII治疗能在单位胰岛素用量较低的情况下,更快、更平稳地控制血糖.CSII是糖尿病合并感染急性期的一种理想的胰岛素输注模式.

关 键 词:感染  2型糖尿病  胰岛素泵  多点注射
文章编号:1008-8199(2007)12-1260-03
收稿时间:2007-06-08
修稿时间:2007-07-01

A comparasion between continuous subcutaneous insulin infusion and multiple daily insulin injection for type 2 diabetes accompanied with infection
MA Jian-hua,WU Jin-dan,XU Xiao-hua,FU Li-yuan,LI Hui-qin,SUN Rui,SHEN Yun,REN Yi-fei,MAO Xiao-ming,QI Shao-kang. A comparasion between continuous subcutaneous insulin infusion and multiple daily insulin injection for type 2 diabetes accompanied with infection[J]. Bulletin of Medical Postgraduate, 2007, 20(12): 1260-1262
Authors:MA Jian-hua  WU Jin-dan  XU Xiao-hua  FU Li-yuan  LI Hui-qin  SUN Rui  SHEN Yun  REN Yi-fei  MAO Xiao-ming  QI Shao-kang
Abstract:Objective: To compare the effects of two different ways of insulin delivery in the treatment of type 2 diabetes mellitus(T2DM) accompanied with infection.Methods:A total of 307 patients with T2DM were divided into 2 groups and received intensive insulin therapy,one group treated by continuous subcutaneous insulin infusion(CSII,n=157),and the other by multiple daily insulin injection(MDI,n=150).Blood glucose levels,days needed for achieving good control,insulin doses and hypoglycemic episodes were compared.Results: Both of the 2 groups reached the target level of blood glucose,but the mean time needed was shorter in the CSII group than in the MDI group(d vs d)(P<0.05).The rate of blood glucose within the target range was higher in the CSII than in the MDI group.The insulin dose at the time of the target level was lower and a better glucose control was noted in the first 5 days of the treatment in the CSII group(P<0.05).There was no significant difference in the incidence of hypoglycemia between the two groups(P>0.05).Conclusion: CSII could achieve faster and better serum glucose control with a lower dose than conventional therapy in the treatment of T2DM patients accompanied with acute infections.
Keywords:Infection   Type 2 diabetes mellitus   Insulin pump   Multiple daily insulin injection
本文献已被 CNKI 万方数据 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号