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重复电针预处理对兔脊髓缺血再灌注损伤的保护作用
引用本文:曾毅,熊利泽,巩固,郑恒兴,王强,朱正华,杨静.重复电针预处理对兔脊髓缺血再灌注损伤的保护作用[J].中国组织工程研究与临床康复,2003,7(2):308-309.
作者姓名:曾毅  熊利泽  巩固  郑恒兴  王强  朱正华  杨静
作者单位:Department of Anesthesiology,Xijing Hospital,Fourth Military Medical University,Department of Anesthesiology,Xijing Hospital,Fourth Military Medical University,Department of Anesthesiology,Xijing Hospital,Fourth Military Medical University,Department of Anesthesiology,Xijing Hospital,Fourth Military Medical University,Department of Anesthesiology,Xijing Hospital,Fourth Military Medical University,Department of Anesthesiology,Xijing Hospital,Fourth Military Medical University,Department of Anesthesiology,Xijing Hospital,Fourth Military Medical University Xi' an 710032,Shaanxi Province,China,Xi' an 710032,Shaanxi Province,China,Xi' an 710032,Shaanxi Province,China,Xi' an 710032,Shaanxi Province,China,Xi' an 710032,Shaanxi Province,China,Xi' an 710032,Shaanxi Province,China,Xi' an 710032,Shaanxi Province,China
基金项目:National Natural Science Foundation of China.(No. 30170907)
摘    要:AIM: To investigate whether pretnatment with repeated electroacupuncture (EA) could induce ischemic tolerance against transient spinal cord ischemia in rabbits. METHODS: 24 male New Zealand white rabbits were randomly assigned to 3 groups(n = 8 each), animals in the control group received no treatment; animals in the SP and EA group received sodium pentobarbitone 30 mg/kg each day for 5 days; animals in EA group were also received electroacupuncture at the Zusanli acupoint 30 min a day for 5 days. 24 hours after the last treatment, spinal cord ischemia was induced by an infrarenal aortic occlusion for 20 min. Hind-limb motor function was determined with the Tarlov criteria at 4,8,12,24 and 48 h after reperfusion. All animals were sacrificed at 48h after reperfusion and the spinal cords(L5) were removed immediately for histopathologic study. RESULTS: The neurologic outcome and histopathology (48 h) in the EA group were significantly better than the control group( P = 0. 006) . CONCLUSION: Pre-ischemic tr


Pretreament with repeated electroacupuncture induced neuroprotection against spinal cord ischemiareperfusion injury in rabbits
Zeng Yl,Xiong Uze,Gong Cu,Zheng Hengxing,Wang Qiang,Zhu Zhenghua,Yang Jing.Pretreament with repeated electroacupuncture induced neuroprotection against spinal cord ischemiareperfusion injury in rabbits[J].Journal of Clinical Rehabilitative Tissue Engineering Research,2003,7(2):308-309.
Authors:Zeng Yl  Xiong Uze  Gong Cu  Zheng Hengxing  Wang Qiang  Zhu Zhenghua  Yang Jing
Institution:Department of Anesthesiology,Xijing Hospital,Fourth Military Medical University,Xi'an 710032,Shaanxi Province,China
Abstract:AIM: To investigate whether pretnatment with repeated electroacupuncture (EA) could induce ischemic tolerance against transient spinal cord ischemia in rabbits. METHODS: 24 male New Zealand white rabbits were randomly assigned to 3 groups(n = 8 each), animals in the control group received no treatment; animals in the SP and EA group received sodium pentobarbitone 30 mg/kg each day for 5 days; animals in EA group were also received electroacupuncture at the Zusanli acupoint 30 min a day for 5 days. 24 hours after the last treatment, spinal cord ischemia was induced by an infrarenal aortic occlusion for 20 min. Hind-limb motor function was determined with the Tarlov criteria at 4,8,12,24 and 48 h after reperfusion. All animals were sacrificed at 48h after reperfusion and the spinal cords(L5) were removed immediately for histopathologic study. RESULTS: The neurologic outcome and histopathology (48 h) in the EA group were significantly better than the control group( P = 0. 006) . CONCLUSION: Pre-ischemic treatment with electroacupuncture significantly reduces spinal cord ischemia-reperfusion injury in rabbits.
Keywords:electro acupuncture  zusanli acupoint  spinal cord ischemia/Zhenjiu Liaofa
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