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地洛他定联合雷尼替丁治疗慢性荨麻疹疗效观察
引用本文:彭振辉,杨闰平,焦来文,李翠华,袁景奕,李政霄. 地洛他定联合雷尼替丁治疗慢性荨麻疹疗效观察[J]. 中国皮肤性病学杂志, 2004, 18(8): 468-469
作者姓名:彭振辉  杨闰平  焦来文  李翠华  袁景奕  李政霄
作者单位:1. 西安交通大学第二医院皮肤科,陕西,西安,710004
2. 北京海军总医院皮肤科,北京,100037
3. 铜川市医院皮肤科,陕西,铜川,727000
摘    要:目的 探讨合并皮肤划痕症的慢性荨麻疹的最佳治疗方案。方法 慢性荨麻疹 80例随机分为两组 ,试验组用地洛他定联合雷尼替丁治疗 ,对照组单用地洛他定治疗 ,连续 4周。结果 试验组有效率为 90 .0 % ,对照组为82 .5 %。治疗 2 8天后两组总积分比较 ,试验组优于对照组 ,有显著性差异 (P <0 .0 0 1)。结论 地洛他定联合雷尼替丁治疗慢性荨麻疹疗效满意 ,安全性好。

关 键 词:地洛他定  雷尼替丁  慢性荨麻疹
文章编号:1001-7089(2004)08-0468-02

The Efficacy of Desloratadine Combined with Ranitidine on Treating Chronic Urticaria
PENG Zhen-hui,YANG Run-ping,JIAO Lai-wen,et al. The Efficacy of Desloratadine Combined with Ranitidine on Treating Chronic Urticaria[J]. The Chinese Journal of Dermatovenereology, 2004, 18(8): 468-469
Authors:PENG Zhen-hui  YANG Run-ping  JIAO Lai-wen  et al
Abstract:Objective To explore the best treatment for chronic urticaria.Methods 80 outpatients with chronic urticaria were randomized to two groups; experimental group was treated with desloratadine and ranitidine, the control group with desloratadine only.Results The effectiveness rate in experimental group was 90.0%, 82.5%for the control group. There were significant differences of total severity scores between two groups after a 28-day duration of treatment(P<0.001), experimental group was superior to the control group.Conclusion Desloratadine combined with ranitidine were effective, safe in the treatment of chronic urticaria.
Keywords:Desloratadine  Ranitidine  Chronic urticaria
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