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复方氯霉素耳用滴丸的制备与临床应用
引用本文:李国忠,汪永干,夏贵华. 复方氯霉素耳用滴丸的制备与临床应用[J]. 中国药师, 2004, 7(7): 536-537
作者姓名:李国忠  汪永干  夏贵华
作者单位:安徽省铜陵市人民医院,铜陵,244000
摘    要:目的: 制备复方氯霉素耳用滴丸并观察其临床疗效.方法: 以聚乙二醇6000为基质,增加甲硝唑作为抗厌氧菌成分制备耳用滴丸剂,并建立质量控制标准.结果: 治疗化脓性中耳炎110耳,总有效率99.1%.结论: 本剂型具有局部药物浓度高,药效时间长等优点,是治疗化脓性中耳炎的理想剂型.

关 键 词:氯霉素  耳用滴丸  质量控制
文章编号:1008-049X(2004)07-0536-02
修稿时间:2004-03-24

Preparation and Clinical Application of Compound Ear Pills of Chloramphenicol
Li Guozhong,Wang Yonggan,Xia Guihua. Preparation and Clinical Application of Compound Ear Pills of Chloramphenicol[J]. China Pharmacist, 2004, 7(7): 536-537
Authors:Li Guozhong  Wang Yonggan  Xia Guihua
Abstract:Objective: To investigate the preparation of compound ear pills of chloramphenicol.Method: Metronidarole was added into the matrix of marcrogol 6000 as its anti anaerobe element,and the standard of quality control was established.Result: 110 cases of patients with purulent otitis media were treated with compound ear pills of chloramphenicol.91 cases of them were cured and 18 were alleviated,one no response.Conclusion: Compound ear pills of chloramphenicol is a ideal preparation to treat purulent otitis media due to its long acting effects and its ability to maintain high concentration in local place.
Keywords:Chloramphenical  Ear pills  Quality control
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