依那普利联合硝苯地平缓释片治疗高血压病疗效观察

目的:比较依那普利、硝苯地平缓释片和依那普利联合硝苯地平缓释片对轻中度高血压病的临床疗效。方法:60例高血压病患者[收缩压为140～180mmHg(1mmHg=0.133kPa),舒张压为90～110mmHg],被随机分为依那普利组(对照a组)、硝苯地平缓释片组(对照b组)和依那普利联合硝苯地平缓释片组(治疗组),经过6周的治疗观察,舒张压下降到正常或下降10～19mmHg以上为有效。结果:三组患者血压均有明显下降。治疗组血压明显下降,总有效率达90%;对照a组总有效率达75%;对照b组总有效率达70%。结论:依那普利联合硝苯地平缓释片治疗高血压病疗效显著。

Effect of enalapril and nifedipine sustained-release tablets in the treatment of hypertension

Objective To compare the clinical effect of enalapril,nifedipine sustained-release tablets and enalapril combined with nifedipine sustained-release tablets in the treatment of mild or moderate hypertension.Method Total 60 patients with essential hypertension（systolic blood pressure of 140~180 mm Hg,diastolic blood pressure of 90~110 mm Hg）were randomly divided into enalapril group（the control group a）,nifedipine sustained-release tablets group（the control group b）and enalapril combined with nifedipine sustained-release tablets group（the treatment group）,the effects was observed after 6 weeks of treatment（diastolic blood pressure fell to normal or decreased 10~19 mm Hg or more was valid）.Results The blood pressure in the three groups were all significantly reduced.The blood pressure decreasing in the treatment group was more obvious than the other two groups.The total effective rate in the treatment group was 90%,in the control group a was 75% and the control group b was 70%.Conclusion Enalapril combined with nifedipine sustained-release tablets has significant effect in the treatment of hypertension.