Induction therapy for elderly patients with acute myeloid leukemia |
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Authors: | Martin Mike G Abboud Camille N |
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Affiliation: | aSection of Bone Marrow Transplantation and Leukemia, Division of Medical Oncology, Siteman Cancer Center, Washington University in Saint Louis, MO 63110, United States |
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Abstract: | Acute myeloid leukemia (AML) is a disease of older adults. Efforts to intensify therapy along traditional avenues have failed to yield improved results. There remains significant clinical equipoise as to how to “induce” patients and whether or not 7 + 3-style regimens improve outcomes over low-dose cytarabine. What is certain is that even in those not receiving active therapy, AML is an exceptionally morbid disease. Diverse interventions are being explored in the management of older patients with AML and the currently available data will be reviewed. |
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Keywords: | Acute myeloid leukemia Review Induction therapy Elderly |
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