The role of colonoscopy and flexible sigmoidoscopy in screening for Colorectal Carcinoma |
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Authors: | Mary Jane Warden MD Dr Nicholas J Petrelli MD Lemuel Herrera MD Arnold Mittelman MD |
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Institution: | (1) Department of Surgical Oncology, Roswell Park Memorial Insitute, 666 Elm Street, 14263 Buffalo, New York |
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Abstract: | Six hundred thirty-two patients were referred to the Colorectal Clinic from February 1983 to February 1986 for screening with
the Pentax 65 cm flexible sigmoidoscope. Forty-nine of these patients (8 percent) had adenomatous polyps. There were 27 males
and 22 females. The mean distance examined by the 65 cm flexible sigmoidoscope was 55 cm. Five patients were excluded from
analysis, leaving 44 patients who underwent colonoscopy to the cecum. At the time of colonoscopy, 15 of the 44 patients (34
percent) had one or more adenomatous polyps beyond reach of the 65 cm flexible sigmoidoscope. The remaining 29 patients who
underwent colonoscopy had no polyps beyond reach of the 65 cm flexible sigmoidoscope. Thirty adenomatous polyps, one invasive
carcinoma of the ascending colon, and one hyperplastic polyp were found in these 15 patients. In summary, 34 percent of patients
found to have adenomatous polyps within reach of the 65 cm flexible sigmoidoscope harbored one or more adenomatous polyps
in the proximal colon at the time of colonoscopy. A positive 65 cm flexible sigmoidoscope examination requires colonoscopy
to identify and remove proximal premalignant lesions, thereby aborting the polyp-cancer sequence. |
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Keywords: | Colonoscopy Sigmoidoscopy Screening Colorectal Carcinoma |
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