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36例下肢动脉硬化闭塞症的介入治疗及疗效观察
引用本文:朱人大,李晓强,孟庆友,朱礼炜,张晔青.36例下肢动脉硬化闭塞症的介入治疗及疗效观察[J].中国综合临床,2010,26(1).
作者姓名:朱人大  李晓强  孟庆友  朱礼炜  张晔青
作者单位:苏州大学附属第二医院血管外科,215000
摘    要:目的 探讨经皮腔内球囊扩张血管成形术(PTA)及血管内支架治疗下肢动脉硬化闭塞症的临床应用价值.方法 总结2008年1~12月应用PTA结合血管内支架成形术治疗36例(41条患肢)下肢动脉硬化闭塞症的效果.结果 PTA即时成功率95.1%(39/41),37条肢体术后临床症状明显改善;2条无明显改善,其中1条术后截肢.临床表现为下肢疼痛消失,皮肤温度变暖,溃疡趋于愈合,踝肱指数由术前0.54±0.11恢复至0.79±0.15.经随访3~15个月,3条股动脉在术后5,6、12个月再次闭塞,1条胫后动脉在术后8个月再次闭塞,通畅率为89.7%(35/39).结论 PTA结合血管内支架置放有助于提高通畅率,操作简便、微创、安全,是治疗下肢动脉硬化闭塞症的有效方法.

关 键 词:动脉硬化闭塞症  支架  介入治疗

Interventional therapy and its efficacy for lower extremity arteriosclerosis occlusive disease of 36 cases
ZHU Ren-da,Li Xiao-qiang,MENG Qing-you,ZHU Li-wei,ZhANG Ye-qing.Interventional therapy and its efficacy for lower extremity arteriosclerosis occlusive disease of 36 cases[J].Clinical Medicine of China,2010,26(1).
Authors:ZHU Ren-da  Li Xiao-qiang  MENG Qing-you  ZHU Li-wei  ZhANG Ye-qing
Abstract:Objective To explore the clinical application of pereutaneous transluminal angioplasty(PTA) and endovascular bracket to treat lower extremity arteriosclorotic occlusion.Methods The clinical data of 36 patients(41 affected limbs)with lower extremity atherosclerotic occlusion who were treated with PTA and bracket implantation from Jan 2008 to Dee 2008 were summarized.Results The initial successful rate of PTA wag 95.1% (39/41).The clinical symptoms were considerably improved in 37 affected limbs,representing of pain disappearing,skin temperature increasing and the healing of refractory ulcer.The index of ankle to brachial significantly increased from 0.54±0.11 to 0.79±0.15(before v.s.after therapy).However,no improvement was observed in 3 affected limbs,and one affected limb Wag re-operated by the amputation.In the following 3 to 15 months.three superficial femorsI arteries were re-obstructed at the 5th,6th,12th month,respectively.One arteria tibialis pesterior was re-obstructed at the 8th month.The cumulative cure rate was 89.7%(35/39).Conclusions PTA is effective in treating atherosclerotic occlusive diseases.The endovascular bracket can increase the cumulative cure rate.PTA and endovascular bracket are safe and effective in treating lower extremity arteriosclerotie occlusion.
Keywords:Arteriosclerotic occlusion  Endovascular bracket  Interventiohal therapy
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