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| 丹参素衍生物的研究进展 | |
| 引用本文： | 王庭芳,郑莉萍,张宁,金磊,吴秋业,张川. 丹参素衍生物的研究进展[J]. 药学实践杂志, 2011, 29(2): 83-88 |
| 作者姓名： | 王庭芳 郑莉萍 张宁 金磊 吴秋业 张川 |
| 作者单位： | 1. 福建中医药大学药学院,福建,福州,350108;第二军医大学药学院新药研究中心,上海,200433;第二军医大学药学院有机化学教研室,上海,200433 2. 福建中医药大学药学院,福建,福州,350108;第二军医大学药学院新药研究中心,上海,200433 3. 第二军医大学药学院新药研究中心,上海,200433 4. 第二军医大学药学院有机化学教研室,上海,200433 |
| 摘 要： | 丹参素是从中草药丹参中提取分离得到的一类酚酸件化合物。具有多种药理活性,对心血管系统具有明显的保护作用。有关丹参素衍生物的研究一直为科研人员所关注,本文对这些文献进行了系统地分析整理,旨在为进一步深入开展丹参素的结构改造和药物创新研究提供依据。 |
| 关 键 词： | 丹参素 衍生物 生物活性 |
| 收稿时间： | 2010-08-25 |
| 修稿时间： | 2011-03-07 |
Progress on Danshensu derivatives |
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| WANG Ting-fang,ZHENG Li-ping,ZHANG Ning,JIN Lei,WU Qiu-ye and ZHANG Chuan. Progress on Danshensu derivatives[J]. The Journal of Pharmaceutical Practice, 2011, 29(2): 83-88 | |
| Authors: | WANG Ting-fang ZHENG Li-ping ZHANG Ning JIN Lei WU Qiu-ye ZHANG Chuan |
| Affiliation: | School of Pharmacy, Fujian University of Traditional Chinese Medicine, Fuzhou 350108, China;New Drug Research Center, School of Pharmacy, Second Military Medical University, Shanghai 200433, China;Department of Organic Chemistry, School of Pharmacy, Second Military Medical University, Shanghai 200433, China;School of Pharmacy, Fujian University of Traditional Chinese Medicine, Fuzhou 350108, China;New Drug Research Center, School of Pharmacy, Second Military Medical University, Shanghai 200433, China;New Drug Research Center, School of Pharmacy, Second Military Medical University, Shanghai 200433, China;New Drug Research Center, School of Pharmacy, Second Military Medical University, Shanghai 200433, China;Department of Organic Chemistry, School of Pharmacy, Second Military Medical University, Shanghai 200433, China;School of Pharmacy, Fujian University of Traditional Chinese Medicine, Fuzhou 350108, China;New Drug Research Center, School of Pharmacy, Second Military Medical University, Shanghai 200433, China |
| Abstract: | Danshensu is the major water-soluble phenolic acids of Danshen. It possessed diverse pharmacological effects, especially the protective effects on cardiovascular diseases. Due to its significant pharmacological activities, synthesis of danshensu derivatives attracted much attention. A systematic review about Danshensu derivatives were carried out in this paper. It was hoped to provide some references to the resource exploitations of the danshensu derivatives. |
| Keywords: | Danshensu derivatives biological activity |
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