A Case of IgG4-Related Disease with Bronchial Asthma and Chronic Rhinosinusitis in Korea |
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| Authors: | Young-Soo Lee Hyo-Jeong Cho Hye-Soo Yoo Yoo-Sub Shin Hae-Sim Park |
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| Affiliation: | Department of Allergy & Clinical Immunology, Ajou University School of Medicine, Suwon, Korea. |
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| Abstract: | IgG4-related disease (IgG4-RD) is characterized by a systemic involvement of tumor-like lesions with IgG4-positive plasmacytes. We experienced a case of IgG4-RD developed in a patient with bronchial asthma (BA) and chronic rhinosinusitis (CRS). A 55-yr-old female patient with BA and CRS complained of both eyes and neck swelling as well as a recurrent upper respiratory infection in recent 1 yr. The serum levels of IgG4, creatinine, and pancreatic enzymes were elevated. A biopsy of the submandibular gland showed an abundant infiltration of IgG4-positive plasmacytes. Her symptoms remarkably improved after the treatment of a systemic steroid that has been maintained without recurrence. We report a rare case of IgG4-RD developed in a patient with BA and CRS.Graphical Abstract | |
| Keywords: | IgG4-Related Disease Asthma Bronchitis Chronic |
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