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Multiple mononeuritis with peripheral blood eosinophilia in a patient with Q fever: An unusual presentation: Case report and review of the literature
Institution:1. Department of Respiratory Medicine, Respiratory Center, Toranomon Hospital, Japan;2. Okinaka Memorial Institute for Medical Research, Japan;3. Department of Infectious Diseases, Keio University School of Medicine, Japan;4. Department of Microbiology, Tokyo Medical University, Japan;5. Department of Infectious Diseases, National Cancer Center Hospital, Japan;6. Center for General Medicine Education, Keio University School of Medicine, Japan;1. Department of General Pediatrics, Tokyo Metropolitan Children’s Medical Center, 2-8-29 Musashidai, Fuchu, Tokyo, 183-8561, Japan;2. Clinical Research Support Center, Tokyo Metropolitan Children’s Medical Center, 2-8-29 Musashidai, Fuchu, Tokyo, 183-8561, Japan;3. Department of Pediatrics, Tama-Hokubu Medical Center, Tokyo Metropolitan Health and Medical Treatment Corporation, 1 Chome-7-1 Aobacho, Higashimurayama, Tokyo, 189-8511, Japan;1. Laboratory of Microbiology, School of Health Sciences, Faculty of Medicine, University of the Ryukyus, Japan;2. Dept. of Food Microbiology and Molecular Biology, National Institute of Nutrition, Viet Nam;1. Department of Hematology and Oncology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan;2. Division of Health Service Promotion, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan;3. Department of Clinical Epidemiology and Health Economics, School of Public Health, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan;4. Department of Health Policy and Informatics, Tokyo Medical and Dental University Graduate School of Medicine, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8510, Japan;5. Department of Cell Therapy and Transplantation Medicine, The University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan
Abstract:Coxiella burnetii is a gram-negative bacterium that typically lives and multiplies within monocytes and macrophages of the host, being the etiologic agent of the zoonosis Q fever. Q fever is usually divided into acute and chronic forms, with a significant percentage of patients being asymptomatic. In the wide spectrum of the disease, neurological involvement seems to be extremely rare and peripheral neuropathy presenting with mononeuritis multiplex is one of the possible presentations with low rates of occurrence. Hereby, we present an unusual case of a 55-year-old male with fever and multiple mononeuritis attributed to Q fever and we summarize a short review of C. burnetii infection.
Keywords:Q fever  Epidedimytis  Eosinophilia  Multiple mononeuritis
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