Assessment of the Relationship between Non-Alcoholic Fatty Liver Disease
and CAD using MSCT |
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Authors: | Duran Efe Fatih Aygün |
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Institution: | 1. Departamento de Radiologia, Faculdade de Medicina, Mevlana University, Konya - Turkey ;2. Departamento de Cirurgia Cardiovascular, Faculdade de Medicina, Mevlana University, Konya - Turkey |
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Abstract: | BackgroundSome risk factors for atherosclerosis are followed by non-alcoholic fatty liver
disease (NAFLD). We wanted to use Multislice computed tomography (MSCT) as
technique for searching relationship between NAFLD and coronary artery disease
(CAD). ObjectiveThe relationship between NAFLD and CAD was investigated using MSCT. MethodsA total of 372 individuals with or without cardiac symptoms who had undergone MSCT
angiography were included in the study. The patients were divided into two groups
according to the presence of NAFLD. Coronary artery segments were visually
evaluated via MSCT angiography. Based on the coronary artery stenosis degree,
those with no or minimal plaques were considered normal, whereas those who had
stenosis of less than 50% and at least one plaque were considered to have
non-obstructive coronary artery disease (non-obsCAD). The patients who had at
least one plaque and coronary artery stenosis of 50% or more were considered to
have obstructive coronary artery disease (obsCAD). NAFLD was determined according
to the MSCT protocol, using the liver density. ResultsAccording to the liver density, the number of patients with non-alcoholic fatty
liver disease (group 1) was 204 (149 males, 54.8%) and with normal liver (group 2)
was 168 (95 males, 45.2%). There were 50 (24.5%) non-obsCAD and 57 (27.9%) obsCAD
cases in Group 1, and 39 (23.2%) non-obsCAD and 23 (13.7%) obsCAD cases in Group
2. ConclusionsThe present study using MSCT demonstrated that the frequency of coronary artery
disease in patients with NAFDL was significantly higher than that of patients
without NAFDL. |
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Keywords: | Fatty Liver Hepatitis |
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